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JCM Accepts, published online ahead of print on 29 November 2006
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J. Clin. Microbiol. doi:10.1128/JCM.02058-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Burkholderia glumae Infection in an Infant with Chronic Granulomatous Disease

Jason B. Weinberg, Barbara D. Alexander, Joseph M. Majure, Larry W. Williams, Jason Y. Kim, Peter Vandamme, and John J. LiPuma*

Division of Infectious Diseases, Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan; Division of Infectious Diseases and International Health, Department of Medicine, Duke University School of Medicine, Durham, North Carolina; Division of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Laboratorium voor Microbiologie, Universiteit Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium

* To whom correspondence should be addressed. Email: jlipuma{at}umich.edu.


   Abstract

An 8-month-old boy developed a necrotic lung mass from which Burkholderia glumae was recovered, leading to the diagnosis of chronic granulomatous disease (CGD). While other Burkholderia species have been identified as important pathogens in persons with CGD, B. glumae has not been previously reported to cause human infection.




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