Diagnosis of Mycoplasma pneumoniaePneumonia in Children

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Article Figures & Data

Table 1.

Results for patients positive for serum IgM antibodies toM. pneumoniae by Platelia μ-capture immunoassay^a

Group and patient no.	Age (yr)	PCR and detection		Culture	Acute-phase serum			Interval (days)	Convalescent-phase serum
Group and patient no.	Age (yr)	Gel	Probe	Culture	Mp IgG^b	Mp IgM^c	CA titer	Interval (days)	Mp IgG^b	Mp IgM^c	CA titer
High IgG titer
1	8.9	Neg.	Pos.	Pos.	>100	4.73	128	26	100	4.64	16
2	10.6	Neg.	Neg.	Neg.	48	1.36	<8	22	52	1.54	<8
3	12.6	Neg.	Neg.	Neg.	90	4.22	256	27	>100	2.44	64
4	3.2	Neg.	Neg.	Neg.	80	2.65	<8	30	90	2.32	<8
5	9.0	Neg.	Neg.	Neg.	43	1.75	32	24	30	1.92	<8
Significant IgG titer increase
6	2.4	ND	ND	ND	54	6.10	64	22	>100	3.15	32
7	9.0	Neg.	Neg.	ND	33	1.64	32	24	95	1.24	16
8	10.1	Neg.	Neg.	Neg.	25	4.83	512	27	65	3.84	128
9	9.3	Neg.	Neg.	Neg.	25	2.36	128	26	50	2.00	16
10	5.3	Neg.	Neg.	Neg.	15	2.14	512	28	51	2.37	64
IgG seroconversion
11	5.3	Pos.	Pos.	Pos.	0	0.64	8	28	27	2.36	8
12	11.8	Pos.	Pos.	ND	1	2.48	<8	32	45	3.39	<8
13	0.5	Pos.	Pos.	Neg.	0	1.26	<8	23	25	2.37	<8
14	10.2	Pos.	Pos.	ND	6	4.03	64	17	25	4.79	16
15	10.5	Neg.	Pos.	Pos.	0	0.47	<8	32	30	4.63	256
16	11.7	Neg.	Pos.	Pos.	6	2.69	128	40	65	3.45	128
17	1.9	Neg.	Pos.	Pos.	0	0.96	<8	26	>100	3.66	<8
18	8.1	ND	ND	ND	4	1.22	ND	31	80	1.58	128
19	8.4	ND	ND	ND	0	0.52	<8	49	55	1.10	<8
Insignificant IgG titer increase^d
20	5.5	Pos.	Pos.	Pos.	6	1.31	<8	26	16	1.42	<8
21	9.1	Pos.	Pos.	Pos.	0	1.61	256	18	7	5.37	512
22	4.1	Neg.^e	Neg.	Pos.	9	0.69	ND	21	10	5.34	ND
23	10.5	ND	ND	ND	4	3.60	128	16	14	4.66	ND
24	7.3	Neg.^e	Neg.	Neg.	4	2.58	256	25	9	2.82	16
Insignificant IgG level
25	5.7	ND	ND	ND	2	1.09	<8	25	3	1.26	<8
26	2.6	Neg.	Neg.	Neg.	6	1.22	<8	24	6	1.23	<8
27	1.4	Neg.	Neg.	Neg.	7	1.93	8	30	7	1.25	<8
28	1.6	Neg.	Neg.	Neg.	0	1.10	<8	25	0	1.11	<8
29	12.8	ND	ND	ND	3	0.62	<8	19	4	1.20	16

↵a Abbreviations: Mp, M. pneumoniae; CA, cold agglutinin; ND, not done; Neg., negative; Pos., positive.
↵b Values are in arbitrary units; see Materials and Methods for definitions.
↵c Specimen value/cutoff control value; positive level, ≥1.00.
↵d IgM result confirmed by Serion IgM test.
↵e Specimen invalid for PCR (not amplified with β-globin primers).