Article Figures & Data
Tables
- Table 1.
Detection of M. tuberculosis complex in respiratory specimens by initial and new versions of AMTDT
Microscopy result Test and result No. of specimens with the following culture result: Positivea Negative Total Positive AMTDT 1 Positive 48 0 48 Negative 0 19b 19 Total 48 19 67 AMTDT 2 Positive 48 0 48 Negative 0 19b 19 Total 48 19 67 Negative AMTDT 1 Positive 34 0 34 Negative 13 296c 309 Total 47 296 343 AMTDT 2 Positive 42 0 42 Negative 5 296c 301 Total 47 296 343 Total AMTDT 1 Positive 82 0 82 Negative 13 315d 328 Total 95 315 410 AMTDT 2 Positive 90 0 90 Negative 5 315d 320 Total 95 315 410 ↵a Only data for specimens with culture-positive results for M. tuberculosis are included.
↵b Nineteen specimens were AMTDT negative and culture positive for NTM.
↵c Seven specimens were AMTDT negative and culture positive for NTM.
↵d Twenty-six specimens were AMTDT negative and culture positive for NTM.
- Table 2.
Comparison of confirmed results for respiratory specimens by AMTDT 1 and AMTDT 2
Test and result No. of specimens with the following confirmed result: Sensitivity (%) Specificity (%) PPV (%) NPV (%) Positive Negative Total AMTDT 1 Positive 82 0 82 83.0 100 100 96.0 Negative 13 315a 328 Total 95 315 410 AMTDT 2 Positive 90 0 90 94.7 100 100 98.4 Negative 5 315a 320 Total 95 315 410 ↵a Twenty-six specimens were culture positive for NTM.
- Table 3.
Detection of M. tuberculosis complex in nonrespiratory specimens by initial and new versions of AMTDT
Microscopy result Test and result No. of specimens with the following culture result: Positivea Negative Total Positive AMTDT 1 Positive 21 0 21 Negative 0 3b 3 Total 21 3 24 AMTDT 2 Positive 21 0 21 Negative 0 3b 3 Total 21 3 24 Negative AMTDT 1 Positive 36 0 36 Negative 11 201c 212 Total 47 201 248 AMTDT 2 Positive 38 0 38 Negative 9 201c 210 Total 47 201 248 Total AMTDT 1 Positive 57 0 57 Negative 11 204d 215 Total 68 204 272 AMTDT 2 Positive 59 0 59 Negative 9 204d 213 Total 68 204 272 - Table 4.
Discrepant results obtained for nonrespiratory specimensa
Type of specimen No. of specimens AMTDT 1 result AMTDT 2 result No. of specimens inhibiting amplification (test) Urine 1 Pos. Neg. 1 (AMTDT 2) Urine 3 Neg. Pos. Urine 2 Neg. Neg. Lymph node 3 Pos. Neg. 3 (AMTDT 2) Lymph node 1 Neg. Pos. Lymph node 1 Neg. Neg. CSF 1 Neg. Neg. CSF 1 Neg. Pos. Ascitic fluid 1 Neg. Pos. Gastric aspirate 1 Neg. Neg. ↵a All specimens were negative forM. tuberculosis by microscopy but positive for M. tuberculosis by culture. Neg., negative; Pos., positive.
- Table 5.
Comparison of confirmed results for nonrespiratory specimens by AMTDT 1 and AMTDT 2
Test and result No. of specimens with the following confirmed result: Sensitivity (%) Specificity (%) PPV (%) NPV (%) Positive Negative Total AMTDT 1 Positive 57 0 57 83.0 100 100 94.0 Negative 11 204a 215 Total 68 204 272 AMTDT 2 Positive 59 0 59 86.8 100 100 98.4 Negative 9 204a 213 Total 68 204 272 ↵a Nine specimens were culture positive for NTM.