DOI: 10.1128/JCM.37.3.748-752.1999
Article Figures & Data
Tables
- Table 2.
Distribution of isolates recovered in each culture system and in combinations of solid and liquid systems
Organism Total no. (%) of isolates recovered witha: Total, all media 960 + solid media 460 TB + solid media Total, 960 Total, 460 TB Total, solid media 960 only 460 TB only Solid media only M. tuberculosiscomplex 132 (100) 121 (92) 128 (97) 102 (77) 119 (90) 105 (79) 4 (3) 11 (8) 3 (2) MAC 172 (100) 160 (93) 136 (79) 147 (86) 123 (72) 106 (62) 36 (21) 12 (5) 3 (2) MOTT 58 (100) 54 (93) 44 (76) 40 (69) 29 (50) 39 (67) 14 (24) 4 (7) 10 (17) All 362 (100) 335 (93) 308 (85) 289 (80) 271 (75) 250 (69) 54 (15) 27 (7) 16 (4) ↵a 960, BACTEC MGIT 960 system; 460 TB, BACTEC 460 TB system.
- Table 3.
Distribution of isolates recovered in culture system and combinations with contaminated cohorts removed from analysis
Organism Total no. of isolates, all media Total no. (%) of isolates recovered witha: 960 + solid media 460 TB + solid media Total, 960 Total, 460 TB Total, solid media M. tuberculosiscomplex 118 111 (94) 114 (97) 101 (86) 108 (92) 95 (81) MAC 160 153 (96) 127 (79) 143 (89) 115 (72) 102 (64) MOTT 53 49 (92) 41 (77) 37 (70) 28 (53) 36 (68) All 331 313 (95) 282 (85) 281 (85) 251 (76) 233 (70) ↵a 960, BACTEC MGIT 960 system; 460 TB, BACTEC 460 TB system.
- Table 4.
TTD of M. tuberculosis, MAC, and all mycobacteria in BACTEC MGIT 960 and BACTEC 460 TB systems
Culture system TTD, days (total no. of isolates detected) for: M. tuberculosiscomplex MAC All mycobacteria Nonpaireda Pairedb, c Nonpaireda Pairedb, d Nonpaireda Pairedb BACTEC 960 14.4 (102) 14.4 (92) 10.0 (147) 9.8 (101) 11.8 (289) 11.1 (213) BACTEC 460 15.2 (119) 13.2 (92) 10.4 (123) 8.4 (101) 12.5 (271) 11.3 (213) - Table 5.
TTD of M. tuberculosis for AFB smear-positive and smear-negative isolates in BACTEC 960 and 460 TB systems
Culture system TTD (range), no. of isolates AFB smear + AFB smear − BACTEC 960, total (n = 102) 10.6 (5–24), 50 18.1 (7–43), 52 BACTEC 460, total (n = 119) 10.8 (3–29), 51 18.4 (6–57), 68 BACTEC 960 (paired) 10.8, 47 18.1, 45 BACTEC 460 (paired) 10.3, 47 16.3, 45 - Table 6.
Breakthrough contamination rates
System % of isolates showing breakthrough contamination All sites (n = 3,330) Site A (n = 558) Site B (n = 494) Site C (n = 679) Site D (n = 628) Site E (n = 323) Site F (n = 648) BACTEC MGIT 960 8.1 9.3 5.4 10.0 14.6 1.8 4.0 BACTEC 460 TB 4.9 5.0 0.6 9.2 7.1 0.9 3.7 Combined solid media 21.1 27.4 0.8 13.2 31.0 5.2 37.8