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Journal of Clinical Microbiology
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Chlamydiology and Rickettsiology

Pooling of Urine Specimens for Detection of Asymptomatic Chlamydia trachomatis Infections by PCR in a Low-Prevalence Population: Cost-Saving Strategy for Epidemiological Studies and Screening Programs

Servaas A. Morré, Chris J. L. M. Meijer, Christian Munk, Susanne Krüger-Kjaer, Jeanette F. Winther, Hans O. Jørgensens, Adriaan J. C. van den Brule
Servaas A. Morré
Department of Pathology, Section of Molecular Pathology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands, and
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Chris J. L. M. Meijer
Department of Pathology, Section of Molecular Pathology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands, and
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Christian Munk
Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, and
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Susanne Krüger-Kjaer
Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, and
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Jeanette F. Winther
Danish Cancer Society, Institute of Cancer Epidemiology, Copenhagen, and
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Hans O. Jørgensens
Defence Medical Training Center, Gentofte, Denmark
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Adriaan J. C. van den Brule
Department of Pathology, Section of Molecular Pathology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands, and
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DOI: 10.1128/JCM.38.4.1679-1680.2000
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ABSTRACT

Pooling, in groups of five, of urine specimens from asymptomatically infected men in a population with 4% prevalence, as determined by case finding, is 100% sensitive and specific and results in a 60.5% reduction in the number of tests needed. Pooling of urine specimens in groups of 10 for the estimation of population-based prevalence is 96.1% sensitive and 100% specific and saves 90% of the test costs.

  • Copyright © 2000 American Society for Microbiology
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Pooling of Urine Specimens for Detection of Asymptomatic Chlamydia trachomatis Infections by PCR in a Low-Prevalence Population: Cost-Saving Strategy for Epidemiological Studies and Screening Programs
Servaas A. Morré, Chris J. L. M. Meijer, Christian Munk, Susanne Krüger-Kjaer, Jeanette F. Winther, Hans O. Jørgensens, Adriaan J. C. van den Brule
Journal of Clinical Microbiology Apr 2000, 38 (4) 1679-1680; DOI: 10.1128/JCM.38.4.1679-1680.2000

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Pooling of Urine Specimens for Detection of Asymptomatic Chlamydia trachomatis Infections by PCR in a Low-Prevalence Population: Cost-Saving Strategy for Epidemiological Studies and Screening Programs
Servaas A. Morré, Chris J. L. M. Meijer, Christian Munk, Susanne Krüger-Kjaer, Jeanette F. Winther, Hans O. Jørgensens, Adriaan J. C. van den Brule
Journal of Clinical Microbiology Apr 2000, 38 (4) 1679-1680; DOI: 10.1128/JCM.38.4.1679-1680.2000
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KEYWORDS

Chlamydia Infections
Chlamydia trachomatis
polymerase chain reaction
urine

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