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Journal of Clinical Microbiology
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CASE REPORTS

Fatal Myocarditis Associated with Acute Parvovirus B19 and Human Herpesvirus 6 Coinfection

Jacques Rohayem, Jürgen Dinger, Rainer Fischer, Karin Klingel, Reinhard Kandolf, Axel Rethwilm
Jacques Rohayem
Institut für Virologie,
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Jürgen Dinger
Klinik für Kinderheilkunde, and
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Rainer Fischer
Institut für Pathologie, Medizinische Fakultät “Carl Gustav Carus,” Technische Universität Dresden, 01307 Dresden, and
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Karin Klingel
Abteilung für Molekulare Pathologie, Institut für Pathologie, Universität Tübingen, 72076 Tübingen, Germany
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Reinhard Kandolf
Abteilung für Molekulare Pathologie, Institut für Pathologie, Universität Tübingen, 72076 Tübingen, Germany
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Axel Rethwilm
Institut für Virologie,
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DOI: 10.1128/JCM.39.12.4585-4587.2001
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ABSTRACT

We report on the case of a healthy young boy who developed a fulminant myocarditis due to acute coinfection with erythrovirus (parvovirus B19) and human herpesvirus 6 (HHV-6) in the absence of an antiviral immune response. We suggest that the HHV-6-induced immunosuppression enhanced dissemination of parvovirus B19, which led to fatal myocarditis.

  • Copyright © 2001 American Society for Microbiology
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Fatal Myocarditis Associated with Acute Parvovirus B19 and Human Herpesvirus 6 Coinfection
Jacques Rohayem, Jürgen Dinger, Rainer Fischer, Karin Klingel, Reinhard Kandolf, Axel Rethwilm
Journal of Clinical Microbiology Dec 2001, 39 (12) 4585-4587; DOI: 10.1128/JCM.39.12.4585-4587.2001

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Fatal Myocarditis Associated with Acute Parvovirus B19 and Human Herpesvirus 6 Coinfection
Jacques Rohayem, Jürgen Dinger, Rainer Fischer, Karin Klingel, Reinhard Kandolf, Axel Rethwilm
Journal of Clinical Microbiology Dec 2001, 39 (12) 4585-4587; DOI: 10.1128/JCM.39.12.4585-4587.2001
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KEYWORDS

Erythema Infectiosum
Herpesviridae Infections
Herpesvirus 6, Human
Myocarditis
Parvovirus B19, Human

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