Article Figures & Data
Tables
- TABLE 1.
Qualitative results obtained by the ELISA and MHA-TPa
IgG ELISA result No. of samples with the following MHA-TP result: Reactive Nonreactive Total Reactive 313 9 322 Nonreactive 0 119 119 Total 313 128 441 ↵a Sensitivity (313 of 313 samples), 100%; specificity (119 of 128 samples), 93%; agreement (432 of 441 samples), 98%.
- TABLE 2.
Qualitative results obtained by the ELISA and FTA-Abs testa
IgG ELISA result No. of samples with the following FTA-ABS test result: Reactive Nonreactive Total Reactive 322 0 322 Nonreactive 2 117 119 Total 324 117 441 ↵a Sensitivity (322 of 324 samples), 99.4%; specificity (117 of 117 samples), 100%; agreement (439 of 441 samples), 99.5%.
- TABLE 3.
Sensitivities and specificities of RPR test, MHA-TP, and IgG ELISA in comparison to results of FTA-Abs test for IgG
Syphilis stagea RPR test MHA-TP IgG ELISA Sensitivityb Specificityc Sensitivity Specificity Sensitivity Specificity PS 23/25 (92) 22/25 (88) 25/25 (100) SS 25/25 (100) 25/25 (100) 25/25 (100) LS 174/179 (97.2) 178/179 (99.4) 179/179 (100) PTS 55/95 (57.9) 88/95 (92.6) 93/95 (97.9) NHS 95/107 (88.8) 107/107 (100) 107/107 (100) ↵a PS, primary syphilis; SS, secondary syphilis; LS, latent syphilis; PTS, past treated syphilis; NHS, no history of syphilis.
↵b The data represent the number of samples positive by the test/number of samples positive by the FTA-Abs test (percent).
↵c The data represent the number of samples negative by the test/number of samples negative by the FTA-Abs test (percent).
- TABLE 4.
Detection of anti-T. pallidum IgM antibodies during early syphilis by the FTA-Abs test for IgM and the ELISA for IgM
Syphilis stagea FTA-Abs test for IgM ELISA for IgM No. of reactive samples/total no. of samples tested (%) No. of nonreactive samples/total no. of samples tested (%) No. of samples with indeterminate results/total no. of samples tested (%) No. of reactive samples/total no. of samples tested (%) No. of nonreactive samples/total no. of samples tested (%) No. of samples with indeterminate results/total no. of samples tested (%) PS 18/25 (72) 1/25 (4) 6/25 (24) 22/25 (88) 2/25 (8) 1/25 (4) SS 17/25 (68) 6/25 (24) 2/25 (8) 19/25 (76) 5/25 (20) 1/25 (4) LS 30/179 (17) 143/179 (80) 6/179 (3.3) 34/179 (19) 143/179 (79.9) 2/179 (1.1) Total 65/229 (28.4) 150/229 (65.5) 14/229 (6.1) 75/229 (32.8) 150/229 (65.5) 4/229 (1.7) ↵a PS, primary syphilis; SS, secondary syphilis; LS, latent syphilis.
