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Bacteriology

Staphylococcal Cassette Chromosome mec and Panton-Valentine Leukocidin Characterization of Methicillin-Resistant Staphylococcus aureus Clones

Shannon M. Moroney, Loree C. Heller, Jesse Arbuckle, Monica Talavera, Ray H. Widen
Shannon M. Moroney
Esoteric Testing, Department of Pathology, Tampa General Hospital, P.O. Box 1289, Tampa, Florida 33601
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  • For correspondence: smoroney@tgh.org
Loree C. Heller
Esoteric Testing, Department of Pathology, Tampa General Hospital, P.O. Box 1289, Tampa, Florida 33601
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Jesse Arbuckle
Esoteric Testing, Department of Pathology, Tampa General Hospital, P.O. Box 1289, Tampa, Florida 33601
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Monica Talavera
Esoteric Testing, Department of Pathology, Tampa General Hospital, P.O. Box 1289, Tampa, Florida 33601
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Ray H. Widen
Esoteric Testing, Department of Pathology, Tampa General Hospital, P.O. Box 1289, Tampa, Florida 33601
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DOI: 10.1128/JCM.01706-06
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    FIG. 1.

    Dendrogram representation and virtual gel image of rep-PCR fingerprints from MRSA isolates. Percentages of similarity are shown at the bottom left of the dendrogram. Clusters A, B, C, and D are shown along with the SCCmec type and PVL status.

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  • TABLE 1.

    Antimicrobial susceptibility profile comparison of MRSA isolates with SCCmec types II and IV

    Antimicrobial agent(s)No. (%) of susceptible isolatesa
    Type II (n = 31)Type IV (n = 19)
    Sulbactam-ampicillin0 (0)0 (0)
    Cefazolin0 (0)0 (0)
    Clindamycin18 (58)18 (95)
    Erythromycin0 (0)2 (11)
    Gentamicin30 (97)18 (95)
    Levofloxacin0 (0)11 (58)
    Linezolid30 (97)19 (100)
    Moxifloxacin4 (13)15 (79)
    Oxacillin0 (0)0 (0)
    Penicillin0 (0)0 (0)
    Rifampin31 (100)19 (100)
    Tetracycline31 (100)17 (89)
    Trimethoprim-sulfamethoxazole30 (97)19 (100)
    Vancomycin31 (100)19 (100)
    • ↵ a Data available for 50 of the 60 patients in the study.

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Staphylococcal Cassette Chromosome mec and Panton-Valentine Leukocidin Characterization of Methicillin-Resistant Staphylococcus aureus Clones
Shannon M. Moroney, Loree C. Heller, Jesse Arbuckle, Monica Talavera, Ray H. Widen
Journal of Clinical Microbiology Mar 2007, 45 (3) 1019-1021; DOI: 10.1128/JCM.01706-06

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Staphylococcal Cassette Chromosome mec and Panton-Valentine Leukocidin Characterization of Methicillin-Resistant Staphylococcus aureus Clones
Shannon M. Moroney, Loree C. Heller, Jesse Arbuckle, Monica Talavera, Ray H. Widen
Journal of Clinical Microbiology Mar 2007, 45 (3) 1019-1021; DOI: 10.1128/JCM.01706-06
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KEYWORDS

Bacterial Toxins
Chromosomes, Bacterial
exotoxins
Leukocidins
methicillin resistance
Staphylococcus aureus

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