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Journal of Clinical Microbiology
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Bacteriology

Cholera Outbreaks Caused by an Altered Vibrio cholerae O1 El Tor Biotype Strain Producing Classical Cholera Toxin B in Vietnam in 2007 to 2008

Binh Minh Nguyen, Je Hee Lee, Ngo Tuan Cuong, Seon Young Choi, Nguyen Tran Hien, Dang Duc Anh, Hye Ri Lee, M. Ansaruzzaman, Hubert P. Endtz, Jongsik Chun, Anna Lena Lopez, Cecil Czerkinsky, John D. Clemens, Dong Wook Kim
Binh Minh Nguyen
1National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
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Je Hee Lee
2International Vaccine Institute, Seoul, Republic of Korea
3School of Biological Sciences, Seoul National University, Seoul, Republic of Korea
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Ngo Tuan Cuong
1National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
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Seon Young Choi
2International Vaccine Institute, Seoul, Republic of Korea
3School of Biological Sciences, Seoul National University, Seoul, Republic of Korea
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Nguyen Tran Hien
1National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
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Dang Duc Anh
1National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
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Hye Ri Lee
2International Vaccine Institute, Seoul, Republic of Korea
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M. Ansaruzzaman
4International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
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Hubert P. Endtz
4International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
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Jongsik Chun
2International Vaccine Institute, Seoul, Republic of Korea
3School of Biological Sciences, Seoul National University, Seoul, Republic of Korea
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Anna Lena Lopez
2International Vaccine Institute, Seoul, Republic of Korea
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Cecil Czerkinsky
2International Vaccine Institute, Seoul, Republic of Korea
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John D. Clemens
2International Vaccine Institute, Seoul, Republic of Korea
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Dong Wook Kim
2International Vaccine Institute, Seoul, Republic of Korea
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  • For correspondence: dwkim@ivi.int
DOI: 10.1128/JCM.02040-08
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ABSTRACT

Vibrio cholerae O1 isolates collected during cholera outbreaks occurring from late 2007 to early 2008 in northern Vietnam were revealed to represent an altered strain containing the RS1 element followed by a CTX prophage harboring El Tor type rstR and classical ctxB on the large chromosome.

  • Copyright © 2009 American Society for Microbiology
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Cholera Outbreaks Caused by an Altered Vibrio cholerae O1 El Tor Biotype Strain Producing Classical Cholera Toxin B in Vietnam in 2007 to 2008
Binh Minh Nguyen, Je Hee Lee, Ngo Tuan Cuong, Seon Young Choi, Nguyen Tran Hien, Dang Duc Anh, Hye Ri Lee, M. Ansaruzzaman, Hubert P. Endtz, Jongsik Chun, Anna Lena Lopez, Cecil Czerkinsky, John D. Clemens, Dong Wook Kim
Journal of Clinical Microbiology Apr 2009, 47 (5) 1568-1571; DOI: 10.1128/JCM.02040-08

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Cholera Outbreaks Caused by an Altered Vibrio cholerae O1 El Tor Biotype Strain Producing Classical Cholera Toxin B in Vietnam in 2007 to 2008
Binh Minh Nguyen, Je Hee Lee, Ngo Tuan Cuong, Seon Young Choi, Nguyen Tran Hien, Dang Duc Anh, Hye Ri Lee, M. Ansaruzzaman, Hubert P. Endtz, Jongsik Chun, Anna Lena Lopez, Cecil Czerkinsky, John D. Clemens, Dong Wook Kim
Journal of Clinical Microbiology Apr 2009, 47 (5) 1568-1571; DOI: 10.1128/JCM.02040-08
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  • Top
  • Article
    • ABSTRACT
    • rstR type.
    • Presence and the location of rstC (RS1).
    • Absence of the tandem repeat of CTX prophage and RS1.
    • Location of RS1-CTX prophage array.
    • Toxin type determination.
    • Multilocus sequence typing (MLST) analysis.
    • Nucleotide sequence accession numbers.
    • ACKNOWLEDGMENTS
    • FOOTNOTES
    • REFERENCES
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KEYWORDS

Cholera
Cholera Toxin
Disease Outbreaks
Vibrio cholerae O1

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