Virology

Sensitive Assay for Quantification of Hepatitis B Virus Mutants by Use of a Minor Groove Binder Probe and Peptide Nucleic Acids

Shuhei Hige, Yoichi Yamamoto, Shigeru Yoshida, Tomoe Kobayashi, Hiromasa Horimoto, Keiko Yamamoto, Takuya Sho, Mitsuteru Natsuizaka, Mitsuru Nakanishi, Makoto Chuma, Masahiro Asaka
DOI: 10.1128/JCM.00731-10

Article Information

DOI 
https://doi.org/10.1128/JCM.00731-10
PubMed 
20926703
Published By 
American Society for Microbiology Journals
History 
  • Received April 8, 2010
  • Returned for modification July 30, 2010
  • Accepted September 29, 2010
  • Published online November 29, 2010.
Copyright & Usage 
Copyright © 2010 American Society for Microbiology

Article Versions

Author Information

  1. Shuhei Hige1*,
  2. Yoichi Yamamoto1,
  3. Shigeru Yoshida2,
  4. Tomoe Kobayashi1,
  5. Hiromasa Horimoto1,
  6. Keiko Yamamoto1,
  7. Takuya Sho1,
  8. Mitsuteru Natsuizaka1,
  9. Mitsuru Nakanishi1,
  10. Makoto Chuma1 and
  11. Masahiro Asaka1
  1. 1Department of Internal Medicine, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo 060-8638
  2. 2Department of Health Sciences, Hokkaido University School of Medicine, Kita-12, Nishi-5, Kita-ku, Sapporo 060-0812, Japan
  • ↵* Corresponding author. Mailing address: Department of Internal Medicine, Gastroenterology Section, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo, 060-8638, Japan. Phone: 81-11-716-1161, ext. 5918. Fax: 81-11-706-7867. E-mail: shuhei-h{at}med.hokudai.ac.jp

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KEYWORDS

Drug Resistance, Viral
Hepatitis B
hepatitis B virus
mutation
Oligonucleotide Probes
Peptide Nucleic Acids

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