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Epidemiology

Differential Circulation of Streptococcus pneumoniae Serotype 6C Clones in Two Israeli Pediatric Populations

Nurith Porat, In Ho Park, Moon H. Nahm, Ron Dagan
Nurith Porat
1Pediatric Infectious Disease Unit, Soroka University Medical Center, and The Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
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  • For correspondence: npurat@bgu.ac.il
In Ho Park
2Departments of Pathology
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Moon H. Nahm
2Departments of Pathology
3Microbiology, University of Alabama at Birmingham, Birmingham, Alabama
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Ron Dagan
1Pediatric Infectious Disease Unit, Soroka University Medical Center, and The Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
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DOI: 10.1128/JCM.01600-10
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    FIG. 1.

    PFGE patterns of chromosomal SmaI digests of Sp6C isolated from children in southern Israel from 1999 to 2008. Strains marked by asterisks were characterized by MLST (Table 1). Lanes 1 to 7, ST3531; lanes 8 to 12, ST1692; lanes 13 and 14, ST4387; lanes 15 and 16, ST367; lanes 17 and 18, ST4386; lanes 19 and 20, ST4439; lane 21, ST4440; lane 22, ST4441; lane 23, ST4381; lane 24, ST4442; lane 25, ST4438; lane 26, ST123; lane 27, ST4601. λ, lambda ladder; R6, S. pneumoniae reference strain used as a molecular weight marker.

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  • TABLE 1.

    Molecular characteristics of Sp6C isolates from Jewish and Bedouin children in southern Israel from 1999 to 2008: distribution by isolation site

    STTotal no. of isolatesaNo. (%)b from: No. from:
    NP MEF Conjunctiva Blood
    JcBdJBJBJBJB
    ST3531528 (14.8)44 (84.6)737140300
    ST16922928 (51.9)1 (1.9)271100000
    ST438755 (9.3)050000000
    ST438655 (9.3)040001000
    ST36762 (3.7)4 (7.7)24000000
    ST443922 (3.7)020000000
    ST443811 (1.9)010000000
    ST12311 (1.9)010000000
    ST460111 (1.9)000100000
    ST4440101 (1.9)00000100
    ST4441101 (1.9)00000001
    ST4442101 (1.9)00000001
    ST438111 (1.9)000100000
        Total10654524942441402
    • ↵ a Number of isolates based on PFGE data and MLST of representative isolates of each PFGE cluster (a total of 18).

    • ↵ b Percentage of each clone in the total number of Sp6C isolates from each ethnic group.

    • ↵ c J, Jewish children.

    • ↵ d B, Bedouin children.

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Differential Circulation of Streptococcus pneumoniae Serotype 6C Clones in Two Israeli Pediatric Populations
Nurith Porat, In Ho Park, Moon H. Nahm, Ron Dagan
Journal of Clinical Microbiology Nov 2010, 48 (12) 4649-4651; DOI: 10.1128/JCM.01600-10

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Differential Circulation of Streptococcus pneumoniae Serotype 6C Clones in Two Israeli Pediatric Populations
Nurith Porat, In Ho Park, Moon H. Nahm, Ron Dagan
Journal of Clinical Microbiology Nov 2010, 48 (12) 4649-4651; DOI: 10.1128/JCM.01600-10
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KEYWORDS

molecular typing
Pneumococcal Infections
Streptococcus pneumoniae

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