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Bacteriology

Nonhemolytic Streptococcus pyogenes Isolates That Lack Large Regions of the sag Operon Mediating Streptolysin S Production

Miho Yoshino, Somay Y. Murayama, Katsuhiko Sunaoshi, Takeaki Wajima, Miki Takahashi, Junko Masaki, Iku Kurokawa, Kimiko Ubukata
Miho Yoshino
1Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan
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Somay Y. Murayama
1Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan
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Katsuhiko Sunaoshi
1Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan
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Takeaki Wajima
2Department of Infectious Diseases, Research Institute, International Medical Center of Japan, Tokyo, Japan
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Miki Takahashi
3Clinical Laboratory, Gunma University Hospital, Maebashi City, Japan
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Junko Masaki
4Clinical Laboratory, Tohoku Rosai Hospital, Sendai City, Japan
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Iku Kurokawa
4Clinical Laboratory, Tohoku Rosai Hospital, Sendai City, Japan
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Kimiko Ubukata
1Laboratory of Molecular Epidemiology for Infectious Agents, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan
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  • For correspondence: ubukatak@lisci.kitasato-u.ac.jp
DOI: 10.1128/JCM.01362-09
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ABSTRACT

Among nonhemolytic Streptococcus pyogenes (group A streptococcus) strains (n = 9) isolated from patients with pharyngitis or acute otitis media, we identified three deletions in the region from the epf gene, encoding the extracellular matrix binding protein, to the sag operon, mediating streptolysin S production.

  • Copyright © 2010 American Society for Microbiology
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Nonhemolytic Streptococcus pyogenes Isolates That Lack Large Regions of the sag Operon Mediating Streptolysin S Production
Miho Yoshino, Somay Y. Murayama, Katsuhiko Sunaoshi, Takeaki Wajima, Miki Takahashi, Junko Masaki, Iku Kurokawa, Kimiko Ubukata
Journal of Clinical Microbiology Jan 2010, 48 (2) 635-638; DOI: 10.1128/JCM.01362-09

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Nonhemolytic Streptococcus pyogenes Isolates That Lack Large Regions of the sag Operon Mediating Streptolysin S Production
Miho Yoshino, Somay Y. Murayama, Katsuhiko Sunaoshi, Takeaki Wajima, Miki Takahashi, Junko Masaki, Iku Kurokawa, Kimiko Ubukata
Journal of Clinical Microbiology Jan 2010, 48 (2) 635-638; DOI: 10.1128/JCM.01362-09
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KEYWORDS

Bacterial Proteins
Operon
Sequence Deletion
Streptococcal Infections
Streptococcus pyogenes
Streptolysins

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