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Journal of Clinical Microbiology
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Epidemiology

Typhoid in Kenya Is Associated with a Dominant Multidrug-Resistant Salmonellaenterica Serovar Typhi Haplotype That Is Also Widespread in Southeast Asia

Samuel Kariuki, Gunturu Revathi, John Kiiru, Doris M. Mengo, Joyce Mwituria, Jane Muyodi, Agnes Munyalo, Yik Y. Teo, Kathryn E. Holt, Robert A. Kingsley, Gordon Dougan
Samuel Kariuki
1Centre for Microbiology Research, Kenya Medical Research Institute, P.O. Box 43640, Nairobi, Kenya
4The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdom
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  • For correspondence: skariuki@kemri.org
Gunturu Revathi
2Aga Khan University Hospital, Nairobi, Kenya
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John Kiiru
1Centre for Microbiology Research, Kenya Medical Research Institute, P.O. Box 43640, Nairobi, Kenya
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Doris M. Mengo
1Centre for Microbiology Research, Kenya Medical Research Institute, P.O. Box 43640, Nairobi, Kenya
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Joyce Mwituria
1Centre for Microbiology Research, Kenya Medical Research Institute, P.O. Box 43640, Nairobi, Kenya
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Jane Muyodi
1Centre for Microbiology Research, Kenya Medical Research Institute, P.O. Box 43640, Nairobi, Kenya
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Agnes Munyalo
1Centre for Microbiology Research, Kenya Medical Research Institute, P.O. Box 43640, Nairobi, Kenya
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Yik Y. Teo
3The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom
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Kathryn E. Holt
4The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdom
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Robert A. Kingsley
4The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdom
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Gordon Dougan
4The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdom
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DOI: 10.1128/JCM.01983-09
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Article Information

DOI 
https://doi.org/10.1128/JCM.01983-09
PubMed 
20392916

Published By 
American Society for Microbiology Journals
History 
  • Received October 7, 2009
  • Returned for modification March 23, 2010
  • Accepted April 2, 2010
  • Published online May 27, 2010.

Copyright & Usage 
Copyright © 2010 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (April 14, 2010).
  • You are viewing the most recent version of this article.

Author Information

  1. Samuel Kariuki1,4*,
  2. Gunturu Revathi2,
  3. John Kiiru1,
  4. Doris M. Mengo1,
  5. Joyce Mwituria1,
  6. Jane Muyodi1,
  7. Agnes Munyalo1,
  8. Yik Y. Teo3,
  9. Kathryn E. Holt4,
  10. Robert A. Kingsley4 and
  11. Gordon Dougan4
  1. 1Centre for Microbiology Research, Kenya Medical Research Institute, P.O. Box 43640, Nairobi, Kenya
  2. 2Aga Khan University Hospital, Nairobi, Kenya
  3. 3The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom
  4. 4The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, United Kingdom
  • ↵* Corresponding author. Mailing address: Centre for Microbiology Research, Kenya Medical Research Institute, P.O. Box 43640-00100, Nairobi, Kenya. Phone: 254 22 718247. Fax: 254 22 711673. E-mail: skariuki{at}kemri.org
  • † Supplemental material for this article may be found at http://jcm.asm.org/ .

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Typhoid in Kenya Is Associated with a Dominant Multidrug-Resistant Salmonellaenterica Serovar Typhi Haplotype That Is Also Widespread in Southeast Asia
Samuel Kariuki, Gunturu Revathi, John Kiiru, Doris M. Mengo, Joyce Mwituria, Jane Muyodi, Agnes Munyalo, Yik Y. Teo, Kathryn E. Holt, Robert A. Kingsley, Gordon Dougan
Journal of Clinical Microbiology May 2010, 48 (6) 2171-2176; DOI: 10.1128/JCM.01983-09

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Typhoid in Kenya Is Associated with a Dominant Multidrug-Resistant Salmonellaenterica Serovar Typhi Haplotype That Is Also Widespread in Southeast Asia
Samuel Kariuki, Gunturu Revathi, John Kiiru, Doris M. Mengo, Joyce Mwituria, Jane Muyodi, Agnes Munyalo, Yik Y. Teo, Kathryn E. Holt, Robert A. Kingsley, Gordon Dougan
Journal of Clinical Microbiology May 2010, 48 (6) 2171-2176; DOI: 10.1128/JCM.01983-09
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KEYWORDS

Anti-Bacterial Agents
Bacterial Typing Techniques
Drug Resistance, Multiple, Bacterial
Salmonella typhi
Typhoid Fever

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