Article Figures & Data
Figures
- Fig. 1.
Correlation between HCV Ag and HCV RNA concentrations. The levels of HCV Ag were highly correlated with those of HCV RNA by the Spearman rank correlation test (r = 0.864; P = 0.0001). x, HCV RNA; y, HCV Ag. The data on the axes are log scaled.
- Fig. 2.
In the cases in which HCV RNA was detected, the group classifications were arbitrarily made by use of HCV RNA levels of ≤105 and >105 IU/ml (groups A and B, respectively). Median HCV core Ag levels of those groups were 25 and 2848 fmol/liter, respectively, and there were significant differences between them (P = 0.0001).
Tables
- Table 1.
Summary of HCV Ag, HCV RNA, and anti-HCV test results
HCV Ag test result No. of samples with the following HCV RNA load (no. of anti-HCV-positive samples/total no.): Not detected <105 IU/ml >105 IU/ml Total Nonreactive 52 (38/52) 6 (1/6) 0 (0/0) 58 (39/58) Reactive 0 (0/0) 104 (104/104) 50 (50/50) 154 (154/154) Total 52 (38/52) 110 (105/110) 50 (50/50) 212 (193/212) - Table 2.
Performances of the HCV Ag and anti-HCV tests compared to the HCV-RNA assaya
Test Sensitivity (%) Specificity (%) PPV (%) NPV (%) Accuracy (%) No. of samples Total positive False negative False positive HCV Ag (Abbott) 96.3 (93.3-99.2) 100 (100-100) 100 (100-100) 89.7 (81.8-97.5) 97.2 (93.4-100) 160 6 0 Anti-HCV (Abbott) 96.3 (93.3-99.2) 26.9 (14.9-38.9) 80.2 (74.6-85.8) 70.0 (49.9-90.1) 79.2 (74.9-82.4) 160 6 38 ↵a Values in parentheses are ranges. PPV, positive predictive value; NPV, negative predictive value.
