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Bacteriology

Large Nosocomial Outbreak of Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Traced to Clonal Expansion of an mgrB Deletion Mutant

Tommaso Giani, Fabio Arena, Guendalina Vaggelli, Viola Conte, Adriana Chiarelli, Lucia Henrici De Angelis, Rossella Fornaini, Maddalena Grazzini, Fabrizio Niccolini, Patrizia Pecile, Gian Maria Rossolini
K. C. Carroll, Editor
Tommaso Giani
aDepartment of Medical Biotechnologies, University of Siena, Siena, Italy
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Fabio Arena
aDepartment of Medical Biotechnologies, University of Siena, Siena, Italy
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Guendalina Vaggelli
bClinical Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy
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Viola Conte
aDepartment of Medical Biotechnologies, University of Siena, Siena, Italy
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Adriana Chiarelli
aDepartment of Medical Biotechnologies, University of Siena, Siena, Italy
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Lucia Henrici De Angelis
aDepartment of Medical Biotechnologies, University of Siena, Siena, Italy
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Rossella Fornaini
cHospital Pharmacy Unit, Florence Careggi University Hospital, Florence, Italy
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Maddalena Grazzini
dHospital Medical Direction, Florence Careggi University Hospital, Florence, Italy
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Fabrizio Niccolini
dHospital Medical Direction, Florence Careggi University Hospital, Florence, Italy
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Patrizia Pecile
bClinical Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy
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Gian Maria Rossolini
aDepartment of Medical Biotechnologies, University of Siena, Siena, Italy
bClinical Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy
eDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy
fDon Carlo Gnocchi Foundation, Florence, Italy
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K. C. Carroll
Roles: Editor
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DOI: 10.1128/JCM.01017-15
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Article Information

DOI 
https://doi.org/10.1128/JCM.01017-15
PubMed 
26202124

Published By 
American Society for Microbiology Journals
History 
  • Received April 21, 2015
  • Returned for modification May 14, 2015
  • Accepted July 14, 2015
  • Published online September 16, 2015.

Copyright & Usage 
Copyright © 2015, American Society for Microbiology. All Rights Reserved.
Editors and / or Reviewers 
  • K. C. Carroll, Editor

Article Versions

  • Accepted Manuscript version (July 22, 2015).
  • You are viewing the most recent version of this article.

Author Information

  1. Tommaso Giania,
  2. Fabio Arenaa,
  3. Guendalina Vaggellib,
  4. Viola Contea,
  5. Adriana Chiarellia,
  6. Lucia Henrici De Angelisa,
  7. Rossella Fornainic,
  8. Maddalena Grazzinid,
  9. Fabrizio Niccolinid,
  10. Patrizia Pecileb and
  11. Gian Maria Rossolinia,b,e,f
  1. aDepartment of Medical Biotechnologies, University of Siena, Siena, Italy
  2. bClinical Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy
  3. cHospital Pharmacy Unit, Florence Careggi University Hospital, Florence, Italy
  4. dHospital Medical Direction, Florence Careggi University Hospital, Florence, Italy
  5. eDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy
  6. fDon Carlo Gnocchi Foundation, Florence, Italy
  • Address correspondence to Gian Maria Rossolini, gianmaria.rossolini{at}unifi.it.
  • T.G. and F.A. contributed equally to this work.

  • Citation Giani T, Arena F, Vaggelli G, Conte V, Chiarelli A, Henrici De Angelis L, Fornaini R, Grazzini M, Niccolini F, Pecile P, Rossolini GM. 2015. Large nosocomial outbreak of colistin-resistant, carbapenemase-producing Klebsiella pneumoniae traced to clonal expansion of an mgrB deletion mutant. J Clin Microbiol 53:3341–3344. doi:10.1128/JCM.01017-15.

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Large Nosocomial Outbreak of Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Traced to Clonal Expansion of an mgrB Deletion Mutant
Tommaso Giani, Fabio Arena, Guendalina Vaggelli, Viola Conte, Adriana Chiarelli, Lucia Henrici De Angelis, Rossella Fornaini, Maddalena Grazzini, Fabrizio Niccolini, Patrizia Pecile, Gian Maria Rossolini
Journal of Clinical Microbiology Sep 2015, 53 (10) 3341-3344; DOI: 10.1128/JCM.01017-15

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Large Nosocomial Outbreak of Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Traced to Clonal Expansion of an mgrB Deletion Mutant
Tommaso Giani, Fabio Arena, Guendalina Vaggelli, Viola Conte, Adriana Chiarelli, Lucia Henrici De Angelis, Rossella Fornaini, Maddalena Grazzini, Fabrizio Niccolini, Patrizia Pecile, Gian Maria Rossolini
Journal of Clinical Microbiology Sep 2015, 53 (10) 3341-3344; DOI: 10.1128/JCM.01017-15
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