ABSTRACT
Recent studies have demonstrated that screening and treatment for toxoplasmosis during gestation result in a decrease of vertical transmission and clinical sequelae. Early treatment was associated with improved outcomes. Thus, laboratory methods should aim for early identification of infants with congenital toxoplasmosis (CT). Diagnostic approaches should include, at least, detection of Toxoplasma IgG, IgM, and IgA and a comprehensive review of maternal history, including the gestational age at which the mother was infected and treatment. Here, we review laboratory methods for the diagnosis of CT, with emphasis on serological tools. A diagnostic algorithm that takes into account maternal history is presented.
- Copyright © 2016 Pomares and Montoya.
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- Top
- Article
- ABSTRACT
- INTRODUCTION
- GENERAL CONSIDERATIONS
- PRINCIPLES AND METHODS AVAILABLE FOR THE DIAGNOSIS OF CONGENITAL TOXOPLASMOSIS
- OVERALL DIAGNOSTIC APPROACH
- DIFFERENCES IN THE DIAGNOSTIC APPROACH TO CT ACCORDING TO THE PRESENCE OR ABSENCE OF MATERNAL SCREENING AND TREATMENT PROGRAMS
- SIMILARITIES IN THE DIAGNOSTIC APPROACH TO CT ACCORDING TO THE PRESENCE OR ABSENCE OF MATERNAL SCREENING AND TREATMENT PROGRAMS
- FUTURE DIRECTIONS
- REFERENCES
- Author Bios
- Figures & Data
- Info & Metrics