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Journal of Clinical Microbiology
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Mycology

Performance of the Cryptococcal Antigen Lateral Flow Assay in Non-HIV-Related Cryptococcosis

Anupop Jitmuang, Anil A. Panackal, Peter R. Williamson, John E. Bennett, John P. Dekker, Adrian M. Zelazny
D. J. Diekema, Editor
Anupop Jitmuang
aMicrobiology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA
cDepartment of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
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Anil A. Panackal
bNational Institute of Allergy and Infectious Diseases, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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Peter R. Williamson
bNational Institute of Allergy and Infectious Diseases, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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John E. Bennett
bNational Institute of Allergy and Infectious Diseases, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
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John P. Dekker
aMicrobiology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA
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Adrian M. Zelazny
aMicrobiology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA
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D. J. Diekema
Roles: Editor
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DOI: 10.1128/JCM.02223-15
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ABSTRACT

The cryptococcal antigen lateral flow assay (CrAg LFA) was evaluated for the diagnosis of cryptococcosis in HIV-negative patients. The sensitivity was excellent, suggesting that this assay can replace conventional testing based on latex agglutination (LA). CrAg LFA and LA titers were correlated but were not directly comparable, with implications for conversion between assays.

  • Copyright © 2016, American Society for Microbiology. All Rights Reserved.
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Performance of the Cryptococcal Antigen Lateral Flow Assay in Non-HIV-Related Cryptococcosis
Anupop Jitmuang, Anil A. Panackal, Peter R. Williamson, John E. Bennett, John P. Dekker, Adrian M. Zelazny
Journal of Clinical Microbiology Jan 2016, 54 (2) 460-463; DOI: 10.1128/JCM.02223-15

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Performance of the Cryptococcal Antigen Lateral Flow Assay in Non-HIV-Related Cryptococcosis
Anupop Jitmuang, Anil A. Panackal, Peter R. Williamson, John E. Bennett, John P. Dekker, Adrian M. Zelazny
Journal of Clinical Microbiology Jan 2016, 54 (2) 460-463; DOI: 10.1128/JCM.02223-15
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