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Journal of Clinical Microbiology
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Bacteriology

Multicenter Evaluation of the Solana Group A Streptococcus Assay: Comparison with Culture

Timothy S. Uphoff, Blake W. Buchan, Nathan A. Ledeboer, Paul A. Granato, Judy A. Daly, Tara N. Marti
Y.-W. Tang, Editor
Timothy S. Uphoff
aMolecular Pathology, Marshfield Labs, Marshfield, Wisconsin, USA
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Blake W. Buchan
bPathology & Laboratory Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
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Nathan A. Ledeboer
bPathology & Laboratory Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
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Paul A. Granato
cLaboratory Alliance of Central New York, Liverpool, New York, USA
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Judy A. Daly
dDepartment of Pathology, University of Utah, Salt Lake City, Utah, USA
ePrimary Children's Medical Center, Salt Lake City, Utah, USA
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Tara N. Marti
aMolecular Pathology, Marshfield Labs, Marshfield, Wisconsin, USA
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Y.-W. Tang
Memorial Sloan-Kettering Cancer Center
Roles: Editor
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DOI: 10.1128/JCM.01268-16
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ABSTRACT

We compared group A Streptococcus (GAS) culture with a rapid helicase-dependent amplification (HDA) method using 1,082 throat swab specimens. The HDA method demonstrated 98.2% sensitivity and 97.2% specificity. GAS prevalence by culture was 20.7%, and it was 22.6% using the HDA method. In 35 min, the HDA method provided rapid, sensitive GAS detection, making culture confirmation unnecessary.

  • Copyright © 2016 Uphoff et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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Multicenter Evaluation of the Solana Group A Streptococcus Assay: Comparison with Culture
Timothy S. Uphoff, Blake W. Buchan, Nathan A. Ledeboer, Paul A. Granato, Judy A. Daly, Tara N. Marti
Journal of Clinical Microbiology Aug 2016, 54 (9) 2388-2390; DOI: 10.1128/JCM.01268-16

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Multicenter Evaluation of the Solana Group A Streptococcus Assay: Comparison with Culture
Timothy S. Uphoff, Blake W. Buchan, Nathan A. Ledeboer, Paul A. Granato, Judy A. Daly, Tara N. Marti
Journal of Clinical Microbiology Aug 2016, 54 (9) 2388-2390; DOI: 10.1128/JCM.01268-16
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