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Bacteriology

Differential Contributions of Specimen Types, Culturing, and 16S rRNA Sequencing in Diagnosis of Prosthetic Joint Infections

Lone Heimann Larsen, Vesal Khalid, Yijuan Xu, Trine Rolighed Thomsen, Henrik C. Schønheyder
Robin Patel, Editor
Lone Heimann Larsen
aDepartment of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark
bCenter for Microbial Communities, Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark
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Vesal Khalid
cDepartment of Orthopaedic Surgery, Aalborg University Hospital, Aalborg, Denmark
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Yijuan Xu
bCenter for Microbial Communities, Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark
dBiotech, Danish Technological Institute, Aarhus, Denmark
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Trine Rolighed Thomsen
bCenter for Microbial Communities, Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark
dBiotech, Danish Technological Institute, Aarhus, Denmark
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Henrik C. Schønheyder
aDepartment of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark
eDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Robin Patel
Mayo Clinic
Roles: Editor
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DOI: 10.1128/JCM.01351-17
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Article Information

DOI 
https://doi.org/10.1128/JCM.01351-17
PubMed 
29444832

Published By 
American Society for Microbiology Journals
History 
  • Received August 22, 2017
  • Returned for modification October 3, 2017
  • Accepted January 15, 2018
  • Published online April 25, 2018.

Copyright & Usage 
Copyright © 2018 Larsen et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.
Editors and / or Reviewers 
  • Robin Patel, Editor, Mayo Clinic

Article Versions

  • Accepted Manuscript version (February 14, 2018).
  • You are viewing the most recent version of this article.

Author Information

  1. Lone Heimann Larsena,b,
  2. Vesal Khalidc,
  3. Yijuan Xub,d,
  4. Trine Rolighed Thomsenb,d and
  5. Henrik C. Schønheydera,e
  6. the PRIS Study Group
  1. aDepartment of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark
  2. bCenter for Microbial Communities, Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark
  3. cDepartment of Orthopaedic Surgery, Aalborg University Hospital, Aalborg, Denmark
  4. dBiotech, Danish Technological Institute, Aarhus, Denmark
  5. eDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark
    1. Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark
      1. Danish Technological Institute, Biotech, Aarhus, Denmark
        1. Department of Chemistry and Bioscience, Aalborg University, Aalborg, Denmark
          1. Department of Health Science and Technology, Faculty of Medicine, Aalborg University
          1. Robin Patel, Editor
          1. Mayo Clinic
          • Address correspondence to Henrik C. Schønheyder, hcs{at}rn.dk.
          • Citation Larsen LH, Khalid V, Xu Y, Thomsen TR, Schønheyder HC, the PRIS Study Group. 2018. Differential contributions of specimen types, culturing, and 16S rRNA sequencing in diagnosis of prosthetic joint infections. J Clin Microbiol 56:e01351-17. https://doi.org/10.1128/JCM.01351-17.

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          Differential Contributions of Specimen Types, Culturing, and 16S rRNA Sequencing in Diagnosis of Prosthetic Joint Infections
          Lone Heimann Larsen, Vesal Khalid, Yijuan Xu, Trine Rolighed Thomsen, Henrik C. Schønheyder the PRIS Study Group
          Journal of Clinical Microbiology Apr 2018, 56 (5) e01351-17; DOI: 10.1128/JCM.01351-17

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          Differential Contributions of Specimen Types, Culturing, and 16S rRNA Sequencing in Diagnosis of Prosthetic Joint Infections
          Lone Heimann Larsen, Vesal Khalid, Yijuan Xu, Trine Rolighed Thomsen, Henrik C. Schønheyder the PRIS Study Group
          Journal of Clinical Microbiology Apr 2018, 56 (5) e01351-17; DOI: 10.1128/JCM.01351-17
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          KEYWORDS

          joint prosthesis
          infection
          biofilm
          diagnosis (microbiology)
          RNA
          ribosomal
          16S
          16S RNA
          biofilms
          diagnostics
          joint infections
          prospective clinical study
          prosthesis infections

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