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Journal of Clinical Microbiology
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More articles from Minireview

  • Human Bacterial Repertoire of the Urinary Tract: a Potential Paradigm Shift
    Minireview
    Human Bacterial Repertoire of the Urinary Tract: a Potential Paradigm Shift

    The aim of this article is to review the human repertoire of bacteria in urine already described by culture and metagenomic techniques and published in the literature. Our study led us to compare this repertoire with other available human repertoires.

    Aurélie Morand, Florent Cornu, Jean-Charles Dufour, Michel Tsimaratos, Jean-Christophe Lagier, Didier Raoult
  • Taxonomic Changes for Human and Animal Viruses, 2016 to 2018
    Minireview
    Taxonomic Changes for Human and Animal Viruses, 2016 to 2018

    The classification of viruses provides the structure necessary to appreciate their biological diversity. Herein, we provide an update to our previous review of changes in viral taxonomy, covering changes between 2016 and 2018.

    Michael J. Loeffelholz, Bradley W. Fenwick
  • An Update on the Novel Genera and Species and Revised Taxonomic Status of Bacterial Organisms Described in 2016 and 2017
    Minireview
    An Update on the Novel Genera and Species and Revised Taxonomic Status of Bacterial Organisms Described in 2016 and 2017

    Recognition and acknowledgment of novel bacterial taxonomy and nomenclature revisions can impact clinical practice, disease epidemiology, and routine clinical microbiology laboratory operations. The Journal of Clinical Microbiology (JCM) herein presents its biannual report summarizing such changes published in the years 2016 and 2017, as published and added by the International Journal of Systematic and...

    Erik Munson, Karen C. Carroll
  • Medical Parasitology Taxonomy Update, 2016–2017
    Minireview
    Medical Parasitology Taxonomy Update, 2016–2017

    Parasite taxonomy continues to change as molecular and morphologic studies enhance our understanding of parasite relatedness. This minireview builds on the information provided in the last taxonomy update in this journal to summarize new and revised clinically relevant human parasite taxonomic changes that have occurred in 2016 and 2017.

    Blaine A. Mathison, Bobbi S. Pritt
  • Name Changes for Fungi of Medical Importance, 2016–2017
    Minireview
    Name Changes for Fungi of Medical Importance, 2016–2017

    This article lists proposed new or revised species names and classification changes associated with fungi of medical importance that were published in the years 2016 and 2017. While many of the revised names listed have been widely adopted without further discussion, some may take longer to achieve more general usage.

    David W. Warnock
  • Cryptococcal Meningitis Diagnostics and Screening in the Era of Point-of-Care Laboratory Testing
    Minireview
    Cryptococcal Meningitis Diagnostics and Screening in the Era of Point-of-Care Laboratory Testing

    Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg), with the recent development and distribution of a point-of-care lateral flow assay. This assay is highly sensitive and specific in cerebrospinal fluid (CSF), but is also sensitive in the blood to detect CrAg prior to meningitis symptoms.

    Radha Rajasingham, Rachel M. Wake, Tafese Beyene, Andrew Katende, Emilio Letang, David R. Boulware
  • Limitations and Confusing Aspects of Diagnostic Testing for Neurologic Lyme Disease in the United States
    Minireview
    Limitations and Confusing Aspects of Diagnostic Testing for Neurologic Lyme Disease in the United States

    In the United States, laboratories frequently offer multiple different assays for testing of cerebrospinal fluid (CSF) samples to provide laboratory support for the diagnosis of central nervous system Lyme disease (CNSLD). Often included among these diagnostic tests are the same enzyme immunoassays and immunoblots that are routinely used to detect the presence of antibodies to...

    Elitza S. Theel, Maria E. Aguero-Rosenfeld, Bobbi Pritt, Patricia V. Adem, Gary P. Wormser
  • Standardization of Nucleic Acid Tests: the Approach of the World Health Organization
    Minireview
    Standardization of Nucleic Acid Tests: the Approach of the World Health Organization

    The first World Health Organization (WHO) international standards (ISs) for nucleic acid amplification techniques were established two decades ago, with the initial focus on blood screening for three major viral targets, i.e., hepatitis C virus, hepatitis B virus, and human immunodeficiency virus 1. These reference materials have subsequently found utility in the diagnosis and monitoring of a wide range of infectious diseases in...

    S. A. Baylis, P. Wallace, E. McCulloch, H. G. M. Niesters, C. M. Nübling
  • Are <em>In Vitro</em> Susceptibilities to Azole Antifungals Predictive of Clinical Outcome in the Treatment of Candidemia?
    Minireview
    Are In Vitro Susceptibilities to Azole Antifungals Predictive of Clinical Outcome in the Treatment of Candidemia?

    The purpose of this review is to critically analyze published data evaluating the impact of azole pharmacokinetic and pharmacodynamic parameters, MICs, and Candida species on clinical outcomes in patients with candidemia. Clinical breakpoints (CBPs) for fluconazole and voriconazole, which are used to determine susceptibility, have been defined by the Clinical and...

    Twisha S. Patel, Peggy L. Carver, Gregory A. Eschenauer
  • Diagnostic Approach to Health Care- and Device-Associated Central Nervous System Infections
    Minireview
    Diagnostic Approach to Health Care- and Device-Associated Central Nervous System Infections

    Health care- and device-associated central nervous system (CNS) infections have a distinct epidemiology, pathophysiology, and microbiology that require a unique diagnostic approach. Most clinical signs, symptoms, and tests used to diagnose community-acquired CNS infections are insensitive and nonspecific in neurosurgical patients due to postsurgical changes, invasive devices, prior antimicrobial exposure, and underlying CNS disease....

    Ryan M. Martin, Lara L. Zimmermann, Mindy Huynh, Christopher R. Polage

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