Results of typing of 188 H. influenzae strains isolated from 30 patients with CF at three different hospitals in Spaina
Patient no. | Sexb | Patient age at isolate collection (yr/mo) | Sampling period (mo) | No. of H. influenzae strainsc | PFGE pattern(s)d | Strain distribution according to PFGE pattern(s) | Persistence of PFGE pattern (mo) | OMP variant(s) | Biotype(s) (no. of strains) |
---|---|---|---|---|---|---|---|---|---|
1 | M | 37/10 | 80 | 15 | 1A, 1B, 2 | 10, 4, 1 | 80, 15, 0 | 1Aa, 1Ab, 1Ac | VI (6)-VIII (2)-VII (2) VI, VI |
2 | F | 18/11 | 39 | 3 | 3, 4 | 2, 1 | 39, 0 | VII, V | |
3 | F | 12/4 | 41 | 18 | 5, 6, 7, 8 | 14, 2, 1, 1 | 26, 10, 0, 0 | 5a(5), 5b, 5c(4), 6a | V, III, II, III |
4 | M | 4/3 | 58 | 7 | 9, 10, 11, 12, 13 | 1, 2, 1, 1, 2 | 0, 3, 0, 0, 2 | II, I, I, II, I | |
5 | M | 15/9 | 60 | 3 | 14, 15 | 2, 1 | 1, 0 | II, III | |
6 | F | 3/10 | 61 | 15 | 16, NT, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26 | 2, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 3 | 3, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 8 | II, VII, II, I, IV, III, II, III, I, III, III, I | |
7 | F | 4/11 | 77 | 15 | 27, 28, 19, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38 | 2, 1, 2, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1 | <1, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 | 19a | I, I, II, II, V, III, III, II, II, III, II, II, II |
8 | M | 11/2 | 41 | 3 | 39, 40, 41 | 1, 1, 1 | II, II, II | ||
9 | M | 21/5 | 12 | 3 | 41, 42, 43 | 1, 1, 1 | III, III, II | ||
10 | F | 16/8 | 49 | 2 | 44, 45 | 1, 1 | I, II | ||
11 | M | 11/9 | 48 | 3 | 46, 47, 48 | 1, 1, 1 | II, II, I | ||
12 | M | 1/6 | 37 | 6 | 49, 41a, 50, 51, 52, 53 | 1, 1, 1, 1, 1, 1 | 41a | VIII, II, VII, III, II, II | |
13 | M | 5/9 | 51 | 5 | 52a, 54, 55, 56 | 1, 2, 1, 1 | 0, 1, 0, 0 | 52a | II, III, II, II |
14 | F | 8/11 | 33 | 1 | 39 | 1 | II | ||
15 | M | 18/1 | 50 | 1 | 57 | 1 | I | ||
16 | F | 6/7 | 41 | 1 | 52 | 1 | VIII | ||
17 | F | 5/10 | 48 | 7 | 58, 59, 60, 61, 62 | 2, 1, 1, 1, 2 | 9, 0, 0, 0, 6 | II, V, I, III, II | |
18 | M | 4/10 | 40 | 4 | 63, 64, NT, 65 | 1, 1, 1, 1 | I, II, III, I | ||
19 | M | 22/6 | 28 | 2 | 66, 67 | 1, 1 | IV, III | ||
20 | F | 3/8 | 38 | 9 | 68, 69, 70, 71, 72, 73 | 1, 2, 2, 1, 2, 1 | 0, 11, 1, 0, 2, 0 | 72a | III, II, I, V, III, II |
21 | M | 1/2 | 47 | 7 | 74, 75, 76, 77, 78, 79, 70 | 1, 1, 1, 1, 1, 1, 1 | I, III, V, III, II, II, I | ||
22 | F | 5/8 | 16 | 5 | 80, 81, 82, 83 | 1, 1, 1, 2 | 0, 0, 0, 2 | 83a | II, II, II, VII, II |
23 | M | 2/3 | 40 | 7 | 84, 85, 86, 87, 88, 89 | 1, 2, 1, 1, 1, 1 | 0, 2, 0, 0, 0, 0 | III, II, III, II, II, I | |
24 | M | 20/2 | 19 | 2 | 90, 91 | 1, 1 | III, III | ||
25 | M | 3 | 17 | 2 | 92, 93 | 1, 1 | II, III | ||
26 | M | 9/7 | 23 | 3 | 94, 95, 96 | 1, 1, 1 | II, II, II | ||
27 | M | 5/6 | 14 | 5 | NT, 97, 98, 99, 100 | 1, 1, 1, 1, 1 | III, V, II, II, III | ||
28 | M | 20/9 | 72 | 27 | 101, 102, 103, 104, 105 | 23, 1, 1, 1, 1 | 72, 0, 0, 0, 0 | 101a | I (20)-II (2)-IV (1), I, I, I, II |
29 | M | 2/5 | 25 | 3 | 106, 107, 108 | 1, 1, 1 | VII, VI, I | ||
30 | M | 6/5 | 20 | 4 | 109, 110, 111 | 2, 1, 1 | 11, 0, 0 | I, I, I |