TABLE 2.

In vitro susceptibilities of Aspergillus spp. obtained with RPMI-2% glucose medium, an inoculum size of 105 UFC/ml, 48 of incubation, and different Tween 20 concentrations

Species (no. of isolates)Tween concn (%)MIC (μg/ml)
Amphotericin BIntraconazoleVoriconazoleTerbinafine
RangeGMaRangeGMRangeGMRangeGM
A. fumigatus (7)50.50-4.01.184.0->8.08.830.25-2.01.1816.0->16.027.13
0.50.25-2.00.690.50->8.03.280.25-4.01.224.0->16.08.27
0.10.25-2.00.570.25->8.01.870.12-2.00.792.0->16.05.94
A. terreus (7)52.0-8.04.562.0-8.04.882.0-8.04.564.04
0.52.0-8.04.270.06-1.00.481.0-4.01.940.50-2.00.88
0.12.0-8.03.740.25-0.500.261.0-4.01.810.25-0.500.41
A. flavus (7)51.0->16.02.972.0-8.04.001.0-2.01.751.0-2.01.28
0.50.50-8.01.940.50-1.00.651.0-2.01.350.12-0.500.33
0.11.0-8.01.700.12-0.500.351.0-4.01.260.03-0.500.14
A. niger (7)50.50-2.00.941.0->8.06.560.12-2.00.691.0-4.02.21
0.50.25-2.00.670.12->8.01.750.12-2.00.670.25-2.00.61
0.10.25-2.00.770.12->8.01.340.12-2.00.690.25-1.00.41
Total (28)50.50->16.01.971.0->8.05.790.12-8.01.601.0->16.04.66
0.50.25-8.01.400.06->8.01.580.12-4.01.210.12->16.01.15
0.10.25-81.290.12->80.690.12-41.060.03->160.64
  • a GM, geometric mean.