TABLE 2.

In vitro susceptibilities of the 10 C. albicans isolates used in this study

Isolate no.MIC (μg/ml)
FluconazoleItraconazoleVoriconazole
24 h48 hInterpretationa24 h48 hInterpretationa24 h48 h
164≥64R0.50.5SDD0.50.5
26464R0.50.5SDD0.250.5
364≥64R0.50.5SDD0.250.25
43232SDD0.250.25SDD0.1250.25
53232SDD0.50.5SDD0.250.25
61616SDD0.250.5SDD0.1250.25
71616SDD0.1250.25SDD0.060.125
80.250.25S0.060.06S0.0150.015
90.1250.125S0.060.06S≤0.0150.015
100.1250.125S0.030.03S≤0.0150.015
  • a R, resistant (fluconazole MIC ≥ 64 μg/ml; itraconazole MIC ≥ 1 μg/ml); SDD, susceptible dose dependent (fluconazole MIC, 16 to 32 μg/ml; itraconazole MIC, 0.25 to 0.5 μg/ml); S, susceptible (fluconazole MIC ≤ 8 μg/ml; itraconazole MIC ≤ 0.125 μg/ml).