TABLE 5.

Univariate and multivariable predictors of mortality at days 3 to 7 after candidemia, Barcelona, Spain, 2002 to 2003a

CharacteristicDeaths (%)Non-deaths (%)Relative Risk (95% CI)P value
Shock22 (61)29 (15)5.5 (3.0-10.0)<0.01
Renal failure17 (46)25 (13)3.9 (2.2-6.7)<0.01
Treatment with antifungal25 (68)188 (96)0.2 (0.1-0.3)<0.01
Catheter removal20 (61)142 (85)0.4 (0.2-0.7)<0.01
High severity of illness category12 (41)25 (19)2.3 (1.2-4.4)0.01
Catheter-related candidemia5 (14)62 (32)0.4 (0.2-1.0)0.03
Intubated15 (43)49 (25)2.0 (1.1-3.6)0.03
Age >65 yr26 (68)100 (50)1.9 (1.0-3.7)0.03
Neutropenia8 (22)19 (10)2.1 (1.1-4.2)0.04
Bacteria in incident culture13 (34)38 (19)1.9 (1.0-3.4)0.04
Hematologic malignancy9 (24)27 (13)1.8 (0.9-3.4)0.1
  • a Excluding C. parapsilosis cases and deaths occurring at days 1 to 2. The multivariable analysis is as follows: for treatment with antifungal, the OR was 0.05, the 95% CI was 0.01 to 0.2, and P was >0.01; for hematologic malignancy, the OR was 3.5, the 95% CI was 1.1 to 10.4, and P was 0.03; and for catheter removal, the OR was 0.3, the 95% CI was 0.1 to 0.9, and P was 0.04. Multivariable analysis results are adjusted for severity of illness category.