TABLE 4.

Performance of IgM and IgG antibody titers against specific antigens in predicting systemic candidiasisa

AntigenIgM testIgG test
% Sensitivity (no. of positive samples/total no. of samples)% Specificity (no. of positive samples/total no. of samples)% Sensitivity (no. of positive samples/total no. of samples)% Specificity (no. of positive samples/total no. of samples)% Positive predictive value (no. of positive samples/total no. of samples)
MET6-125 (15/60)66.7 (16/24)65 (39/60)83.3 (20/24)90.7 (39/43)
MET6-218.3 (11/60)66.7 (16/24)60 (36/60)54.2 (13/24)76.6 (36/47)
NOT563.3 (38/60)79.2 (19/24)85 (51/60)87.5 (21/24)94.4 (51/54)
SET165 (39/60)75 (18/24)98.3 (59/60)66.7 (16/24)88.1 (59/67)
RBT441.7 (25/60)83.3 (20/24)98.3 (59/60)62.5 (15/24)86.8 (59/68)
IPF916268.3 (41/60)79.2 (19/24)96.7 (58/60)50 (12/24)82.9 (58/70)
CAR143.3 (26/60)79.2 (19/24)90 (54/60)75 (18/24)90 (54/60)
GAP110 (6/60)79.2 (19/24)91.7 (55/60)87.5 (21/24)94.8 (55/58)
ENO146.7 (28/60)79.2 (19/24)98.3 (59/60)70.8 (17/24)89.4 (59/66)
BGL223.3 (14/60)70.8 (17/24)95 (57/60)75 (18/24)90.5 (57/63)
FBA136.7 (22/60)79.2 (19/24)93.3 (56/60)91.7 (22/24)96.6 (56/58)
MUC1-113.3 (8/60)75 (18/24)96.7 (58/60)50 (12/24)82.9 (58/70)
MUC1-220 (12/60)83.3 (20/24)86.7 (52/60)54.2 (13/24)82.5 (52/63)
PGK1-144.1 (26/59)*95.6 (22/23)*72.9 (43/59)*56.5 (13/23)*81.1 (43/53)*
PGK1-220.3 (12/59)*87.0 (20/23)*62.7 (37/59)*52.2 (12/23)*52.2 (37/48)*
  • a * indicates that one patient with systemic candidiasis and one control did not have sufficient sera to test against PGK1-1 and PGK1-2.