TABLE 2.

Demographics, clinical characteristics, and outcomes of candidemia cases by select species, Barcelona, Spain, 2002 to 2003

CharacteristicAll casesaC. albicansC. glabrataC. tropicalisC. kruseiC. parapsilosis
Median age (range)63 (0-90)66 (0-90)68 (0-90)66 (22-86)60 (29-79)36 (0-80)
Male203 (59)101 (58)21 (72)22 (67)7 (58)43 (55)
Age <1 yr32 (9)11 (6)1 (4)1 (3)019 (24)
Outpatientb37 (11)23 (13)4 (14)2 (7)06 (8)
Median days in hospital until candidemia (range)20 (0-288)20 (1-268)14 (0-64)16 (3-58)18.5 (4-34)28 (0-288)
Malignancy123 (36)61 (35)6 (20)18 (58)9 (75)21 (27)
Immunosuppressive therapy130 (39)64 (37)6 (21)16 (53)9 (75)29 (38)
Neutropeniac38 (11)10 (6)08 (26)8 (67)9 (12)
Renal failure117 (34)72 (41)11 (38)11 (36)3 (25)16 (21)
Transplant patient26 (8)3 (2)05 (15)2 (17)12 (15)
HIV infection15 (4)12 (7)1 (4)002 (3)
In ICU at diagnosis115 (33)59 (37)7 (28)10 (33)4 (33)31 (42)
Previous Candida colonization111 (33)75 (43)11 (38)11 (34)1 (10)9 (12)
Previous surgery157 (46)84 (49)14 (48)13 (42)4 (33)36 (46)
Vascular catheter at diagnosis302 (89)146 (86)24 (83)28 (88)12 (100)76 (97)
TPNd125 (40)57 (38)7 (27)7 (23)3 (25)43 (57)
Catheter related108 (31)53 (31)3 (10)7 (22)2 (17)42 (54)
Prior antibiotic therapy298 (88)156 (91)21 (72)26 (84)10 (91)70 (91)
Prior antifungal therapy57 (17)12 (7)7 (21)4 (13)9 (75)20 (26)
Death by day 3-774 (22)42 (24)9 (31)11 (33)2 (17)5 (6)
Overall mortality150 (44)83 (47)14 (50)19 (59)5 (46)22 (28)
Total cases345 (100)176 (51)29 (8)34 (10)12 (4)78 (23)
  • a All data are given as no. (%), except where a range is indicated.

  • b Outpatient, cases with positive blood culture either prior to or at ≤2 days of hospitalization.

  • c Absolute neutrophil count less than 0.5 × 109/liter.

  • d TPN, total parenteral nutrition.