TABLE 1.

Predisposing factors among 472 patientsa with invasive GAS infections

Predisposing factorsn (%)
Predisposing factors (≥1)348 (74)
Skin lesions149 (32)
Cancer62 (13)
Diabetes mellitus52 (11)
Alcoholism44 (9)
Immune incompetenceb39 (8)
Chronic heart or lung disease26 (6)
NSAIDc29 (6)
IDUd23 (5)
Peri-/Postoperative16 (3)
  • a Information regarding underlying diseases was available for 472 (95%) of the 496 cases of invasive GAS infections.

  • b Immune incompetence, received immunosuppressive treatment or positive for human immunodeficiency virus.

  • c NSAID, nonsteroid anti-inflammatory drug.

  • d IDU, intravenous drug use.