TABLE 3.

In vitro susceptibilities of 351 Candida bloodstream isolates to amphotericin B, flucytosine, and fluconazolea

SpeciesNo. of isolates (%)Amphotericin BFlucytosineFluconazole
RangeGMMIC90RangeGMMIC90RangeGMMIC90
C. albicans 178 (51)0.03-0.250.060.120.125-40.170.250.125-80.160.25
C. parapsilosis 81 (23)0.03-0.250.190.250.125-10.150.250.125->640.411
C. tropicalis 36 (10)0.06-0.50.090.120.125-0.50.150.250.125->640.280.5
C. glabrata 31 (9)0.03-0.50.190.250.125-0.250.140.252->646.316
C. krusei 14 (4)0.25-0.50.30.52-42.43432->645264
Others11 (3)0.03-0.250.080.250.125-40.4120.125-161.0616
Total351 (100)0.03-0.50.080.250.125-40.180.50.125->640.398
  • a Susceptibility data in micrograms per milliliter. Data are from 345 cases with 351 isolates (6 polyfungal candidemias). Results are reported as MIC ranges, geometric mean (GM) MIC values, and MIC90s.