TABLE 1.

Demographic characteristics of case patients and negative control patients by infection type

CharacteristicNo. (%) of patientsa
Aspergillosis (n = 22)Candida infection (n = 23)Other mold infection (n = 17)
Gender
    No. of males16 (73)12 (52)9 (53)
    No. of females6 (27)11 (48)8 (47)
Age (yr) (median [range])60 (10-78)55 (23-81)51 (22-73)
Underlying disease
    Hematological22 (100)11 (48)17 (100)
    Solid tumor0 (0)12 (52)0 (0)
Bone marrow transplantation12 (55)2 (9)9 (53)
Allogeneic hematopoietic stem cell transplant donor type12 (55)2 (9)7 (41)
Site of IFI
    Lung21 (96)4 (23)
    Sinus1 (5)5 (29)
    Blood23 (100)2 (12)
    Skin6 (35)
Antifungal therapy22 (100)21 (91)17 (100)
Graft-versus-host disease8 (36)1 (4)5 (29)
Neutropenia during prior mo12 (55)9 (39)9 (53)
Neutropenia at infection onset5 (23)6 (26)6 (35)
Use of steroids before infection15 (68)9 (39)11 (65)
Use of steroids during infection17 (77)9 (39)11 (65)
Immunotherapy18 (82)10 (44)13 (77)
White blood cell count2 (9)2 (9)4 (24)
Granulocyte-macrophage colony-stimulating factor4 (18)2 (9)4 (24)
Granulocyte colony-stimulating factor16 (73)9 (39)12 (71)
Gamma interferon1 (5)1 (4)6 (35)
Breakthrough20 (91)11 (48)13 (77)
  • a Data represent numbers (percentages) of patients except where otherwise indicated.