TABLE 4.

MBL detection by CD: results of SN, SP, PPV, and NPV stratified into seven groups according to pathogen species and MBL type produced

GroupVol (μl)Ceftazidime resultImipenem result
EDTAMPAMACEDTAMPAMAC
Breakpointa (mm)SN (%)SP (%)Breakpoint (mm)SN (%)SP (%)Breakpoint (mm)SN (%)SP (%)Breakpoint (mm)SN (%)SP (%)Breakpoint (mm)SN (%)SP (%)Breakpoint (mm)SN (%)SP (%)
General2-b--5.08579---2.08063------
43.085746.083742.085422.08732------
65.0787410.085632.085214.07858------
86.0808411.083682.093214.08053------
109.0839014.085686.087375.08063------
Acinetobacter spp.2------------1.0701001.080100
43.07083---------------
64.07050---3.08017---------
84.080338.08050------------
104.0801713.08033------------
Pseudomonas2---9.0931005.082833.08250------
    aeruginosa47.0938311.093836.093835.082831.08267---
68.09610016.0891008.089676.082833.08633---
88.09610014.0961009.093507.0861004.08233---
109.0968314.0968311.089678.0821006.08233---
Enterobacterial2---------3.0100100------
4---------4.0100100------
6---1.08629---4.0100100------
8---1.086142.086434.0100100------
10---3.0100293.086435.0100100------
IMP2---8.086895.08295---------
43.089746.086744.086841.08221------
64.0896310.086636.082741.08221------
85.0866311.086688.082641.08616------
107.0866814.08668---1.08616------
SPM2---13.0100100---3.090793.090.089.0
47.0909515.0100100---5.0100951.0906810.0100100
68.010010017.01001003.0100895.0100905.01006812.0100100
89.010010017.01001006.0100847.0100956.090689.010084
109.01009018.0100958.080898.0100908.0806814.0100100
VIM2---------4.083100------
4---------4.08390------
6---1.08311---5.08390------
8---1.083112.083215.010068------
10------3.083165.010063------
  • a Breakpoint is the increase in the size of the inhibition zone.

  • b -, no breakpoints yielded SN results higher than 80%.