TABLE 1.

Patient characteristics

CharacteristicPatients with:Totalb
Proven IAProbable IAPossible IFINo IA
No. of episodes9213125149 (96)
No. of deaths8141124
No. of autopsies600814
Age (yr)
    Mean4647434545
    Median4247404746
    Range19-6940-5318-6817-7417-74
Sex (no. male/no. female)6/32/012/182/43102/47 (67/29)
No. with diseasea
    AML3154857 (29)
    ALL1042631 (19)
    CML012811 (9)
    MDS3021116 (14)
    NHL2002830 (21)
    AA00022 (2)
    Other00022 (2)
No. with allografts4264456
Duration of episode (days)
    Mean12692785057
    Median13592573743
    Range36-23450-13435-17211-18111-234
No. with host factor:
    Neutropenia71886102
    Fever6173751
    GVHD2251726
    Steroid2142835
    None1001819
Duration of neutropenia (days)
    Mean6310421621
    Median3710181415
    Range0-2050-200-1620-1200-205
No. of samples tested
    PCR154251469261,251
        Mean (per episode)17.112.511.27.48.4
        Median (per episode)1713966
        Range (per episode)7-326-194-243-263-32
    GM155241409141,233
        Mean (per episode)17.212.010.87.38.3
        Median (per episode)1812956
        Range (per episode)7-305-195-242-262-30
    BDG158241479141,243
        Mean (per episode)17.612.011.37.38.3
        Median (per episode)1912966
        Range (per episode)7-315-196-243-233-31
  • a AML, acute myelogenous leukemia; ALL, acute lymphocytic leukemia; CLL, chronic nyelogenous leukemia; MDS, myelodysplastic syndrome; NHL, non-Hodgkin lymphoma; AA, aplastic anemia.

  • b Values in parentheses are numbers of patients. Other values refer to numbers of episodes.