TABLE 3.

Distribution of vacA and cagA allelic types according to histopathological findings in the antra of 276 dyspeptic patients

Histopathological findingsbNo. (%) with vacA and cagA results
s1/m1s1/m2s2/m1s2/m2MixedIncaNegative
cagA+cagAcagA+cagAcagA+cagAcagA+cagAcagA+cagAcagA+cagAcagA+cagA
Nonatrophic gastritis
    CG (n = 48)9 (19)2 (4)4 (8)6 (13)001 (2)04 (8)03 (6)01 (2)18 (38)
    CAG (n = 185)80 (43)2 (1)36 (20)4 (2)2 (1)010 (6)10 (6)6 (3)4 (2)6 (3)4 (3)2 (1)19 (10)
Atrophic gastrits
    CAAG (n = 24)9 (38)1 (4)10 (42)2 (8)00001 (4)00001 (4)
    CAAGI (n = 17)9 (53)03 (18)000001 (6)01 (6)003 (18)
Malignant lesions
    Adenocarcinoma (n = 1)000000001 (100)00000
    MALT lymphoma (n = 1)1 (100)0000000000000
Total (n = 276)108 (39)5 (2)53 (19)12 (4)2 (1)011 (4)10 (4)13 (5)4 (1)10 (4)4 (1.4)3 (1)41 (15)
  • a vacA gene was incomplete (Inc) to yield a detectable PCR product for the vacA s or m region.

  • b Abbreviations: CG, chronic gastritis; CAG, chronic active gastritis; CAAG, chronic active atrophic gastritis; CAAGI, chronic active atrophic gastritis with intestinal metaplasia; MALT, mucosa-associated lymphatic tissue.