TABLE 2.

Analytical sensitivities, specificities, and predictive values of IgM detection in relation to PCR resultsa

AssayNo. (%) of serum specimensPPV (%)NPV (%)% Agreement
Case sera testing positive (n = 31)bControl sera testing negative (n = 96)
AniLabsystems24 (77)88 (92)24/32 (75)88/95 (93)88.1
Biotest16 (52)91 (95)16/21 (73)91/106 (86)84.3
CFT20 (65)93 (97)20/23 (87)93/104 (89)89.0
Diagnosys18 (58)90 (94)18/24 (75)90/103 (87)85.0
ImmunoCard12 (48)c76 (79)12/32 (38)76/89 (85)72.7
ImmunoWell11 (35)92 (96)11/15 (73)92/112 (82)81.1
Novum22 (71)47 (49)22/71 (31)47/56 (84)54.3
Platelia16 (52)94 (98)16/18 (89)94/109 (86)86.6
Ridascreen11 (35)96 (100)11/11 (100)96/116 (83)84.3
Serion classic15 (48)91 (95)15/20 (75)91/107 (86)83.5
SeroMP22 (71)84 (88)22/34 (65)84/93 (92)83.5
SerodiaMycoII20 (65)84 (88)20/32 (63)84/95 (88)81.9
Virotech14 (45)92 (96)14/18 (78)92/109 (84)83.5
  • a Equivocal results were considered negative.

  • b More than 6 days after disease onset.

  • c n = 25.