TABLE 1.

Target genes in multilocus sequence typing scheme for S. uberis

GeneEnzymeFunctional category
cpn60 Chaperonin or heat shock protein 60Protein synthesis and metabolism (housekeeping)
gapC Glyceraldehyde-3-phosphate dehydrogenaseCell surface protein synthesis (housekeeping)a
oppF Oligopeptide permease homologAmino acid acquisition (housekeeping/virulence)b
pauA Plasminogen activator ACleavage of plasminogen (virulence gene)c
sodA Superoxide dismutaseAntioxidant enzyme (housekeeping)
tuf Elongation factor TuGTP binding protein (housekeeping)
  • a Considered as target for vaccine development (9, 30).

  • b Necessary for growth in milk (43).

  • c Considered as target for vaccine development (8, 31).