TABLE 2.

Antimicrobial susceptibilities of S. pneumoniae isolates from CF patients followed at Ramón y Cajal University Hospital in Madrid, Spain

Antimicrobial agentMIC (μg/ml)% of isolates
Range5090SusceptibleIntermediateResistant
Penicillin≤0.03-41227.027.046.0
Ampicillin≤0.06-414a
Amoxicillin-clavulanate≤0.5->4/2≤0.51/0.594.02.04.0
Cefuroxime≤0.12->82437.512.550.0
Cefotaxime≤0.03->40.5166.629.04.4
Cefepime≤0.06->21243.831.225.0
Meropenem≤0.12-10.5148.039.512.5
Vancomycin≤0.25-0.5≤0.250.5100.000
Teicoplanin≤0.25≤0.25≤0.25100.000
Erythromycin≤0.25->1>1>158.4041.6
Clarithromycin≤0.25->16≤0.25>1662.52.035.5
Clindamycin≤0.12->1≤0.12>170.94.125.0
Tetracycline≤0.25->4>4>441.7058.3
Ciprofloxacin≤0.06-211
Levofloxacin≤0.25-211100.000
SxTb≤0.5/9->2/38>2/38>2/3833.44.162.5
Chloramphenicol≤2->4>4>452.0048.0
Rifampin≤0.5->2<0.5<0.598.002.0
  • a —, no NCCLS criteria available.

  • b SxT, trimethoprim-sulfametoxazole.