TABLE 3.

Summary of sensitivities, specificities, positive predictive values, and negative predictive values of the boronic acid tests using different antibiotic substrates in the phenotypic detection of KPC-possessing isolates

Antibiotic used in boronic acid disk testNo. (%) of isolates confirmed by PCR as:Test performancea (%)
Possessing KPC (n = 57)Not possessing KPC (n = 106)SensitivitySpecificityPPVNPV
Imipenem57 (100)0 (0)100100100100
Meropenem57 (100)0 (0)100100100100
Ertapenem57 (100)5 (4.7)10095.391.9100
Cefepime57 (100)0 (0)100100100100
Cefotetan57 (100)42 (39.6)10060.457.6100
Cefoxitin55 (96.5)32 (30.2)96.569.863.297.4
Cefotaxime38 (66.7)19 (17.9)66.782.166.782.1
Ceftazidime11 (19.3)13 (12.3)19.387.745.866.9
  • a PPV, positive predictive value; NPV, negative predictive value.