TABLE 1.

Antimicrobial susceptibilities, onset of infections, and isolation sites of CTX-M-14-producing E. coli strains from the CHRa

Strain (n)No. of strains (%)
ResistancebOnset of infectioncSite of isolation
GENSXTCIPCommunityHospitalNursing homeUrineBloodOther sites
CTX-M-14 (87)6 (7)10 (12)79 (91)62 (72)24 (28)1 (1)78 (90)7 (8)2 (2)
CTXM14A (59)1 (2)3 (5)58 (98)47† (80)11† (19)1 (2)59† (100)0† (0)0 (0)
CTXM14AR (8)1 (13)1 (13)8 (100)4 (50)4 (50)0 (0)4 (50)4 (50)0 (0)
CTXM14NR (20)4* (20)6* (30)13* (65)11 (55)9 (45)0 (0)15 (75)3 (15)2 (10)
  • a CTXM14A and CTXM14AR indicate clusters with >80% similarity. CTXM14NR indicates strains not related to CTXM14A and CTXM14AR. *, P < 0.05 (significantly different from CTXM14A and CTXMAR [Fisher exact test]); †, P < 0.05 (significantly different from CTXMAR and CTXMNR [Fisher exact test]).

  • b GEN, gentamicin; SXT, trimethoprim-sulfamethoxazole; CIP, ciprofloxacin.

  • c Community-onset infections were diagnosed in individuals who did not have a hospitalization in the preceding 3 months and who were either outpatients or admitted patients who had first positive cultures obtained within 48 h of hospital admission. Other hospitalized patients and all residents of nursing homes were deemed to have nosocomial infections.