TABLE 1.

Caspofungin MIC distribution for 694 isolates of C. albicans: influence of test medium, reading time, and end point criterion

Test mediumEnd point inhibition criterionIncubation time (h)No. of isolates at MIC (μg/ml):
0.0070.0150.030.060.120.250.51248>8
RPMIComplete240224164399908002a05a
48021274303228635001a6a
Partial2454127338156120004a3a
489133348180132114a3a
AM3Complete243521638151402a1a3a1a1a
48970457138942b1a1a2a02a
Partial24109422148801a2a2a2a
487440619212212a1a4a
  • a Glucan synthesis mutant.

  • b One of two isolates is a glucan synthesis mutant.