TABLE 1.

Index of reactivity of heat-treated and not treated soluble antigens from suspensions of clinical and reference strains of Cryptococcus spp. in the Platelia Aspergillus assaya

Strain designationSite of isolationIdentificationIndex of reactivity in expt:
1 (no heat treatment)2 (no heat treatment)3 (heat treatment)
44CSF C. neoformans 4.8>53.4
101Blood culture C. neoformans 4.7>53.1
294Blood culture C. neoformans >5>5>5
545CSF C. neoformans 3.8>53.3
590Urine C. neoformans serotype A>5>5>5
648Blood culture C. neoformans serotype A4.1>5>5
681CSF C. neoformans serotype A3.6>5>5
861CSF C. neoformans 4.8>53.4
1451CSF Cryptococcus sp. 5>53.4
1782BAL C. neoformans serotype D>5>5>5
1829Blood culture C. neoformans serotype A3.5>5>5
2323Toe nail C. laurentii >5>5>5
2500bBlood culture C. neoformans serotype A4.9>53.5
2501bSputum C. neoformans serotype A4>5>5
NIH 68Reference strain C. neoformans serotype AND3.12.6
NIH 112BReference strain C. neoformans serotype BND>5>5
NIH 52DReference strain C. neoformans serotype DND2.82.2
CDC B.238Reference strain C. neoformans serotype CND>5>5
Cap 67Reference strain C. neoformans non typableND>53.5
  • a CSF, cerebrospinal fluid; BAL, bronchoalveolar lavage; ND, not done. Experiments 2 and 3 were performed on the same antigenic extracts.

  • b Isolates 2500 and 2501 were obtained from the patient described in this paper.