TABLE 3.

Comparison of GP5+/6+ PCR and MGP PCR systems for plasmid controls and for all concordant (i.e., positive by both GP5+/6+ and MGP PCRs) clinical samplesa

HPV typeGP5+/6+ PCR systemMGP PCR systemNo. of concordant positive samples
Mean ratio for no. of copies:Mean cutoffMFI of positive samples (median)Mean ratio of samplesMean ratio for no. of copies:Mean cutoffMFI of positive samples (median)Mean ratio of samples
5005PositiveNegative5005PositiveNegative
1634.918.617557 (587)32.80.6767.243.014991 (1,017)73.40.69191
1815.83.311130 (129)11.80.5020.510.310153 (130)16.50.6362
316.10.51099 (91)9.90.2226.33.8595 (103)19.10.4366
334.10.61053 (51)5.30.2016.84.8557 (38)11.40.4144
351.50.71619 (19)1.10.523.52.31329 (29)2.00.642
35v0.60.31031 (28)3.10.212.31.4545 (42)9.10.4018
393.40.72075 (71)3.90.528.55.01657 (52)3.60.6616
456.80.71095 (86)9.50.4616.63.37101 (85)13.80.6334
512.90.441056 (55)5.60.3026.113.510115 (110)12.00.3629
524.10.611179 (106)15.40.50172.3108.581147 (1,118)149.00.6635
5654.23.810374 (440)37.40.21118.868.45357 (371)71.30.4146
583.90.51031 (32)3.10.247.11.7543 (37)5.30.4914
5943.819.410286 (323)28.90.4736.314.114350 (147)26.80.3621
6618.33.610352 (274)35.00.5736.311.412411 (411)29.10.3440
680.50.41010 (10)1.00.405.73.41239 (39)3.90.341
6bNDND3576 (63)2.70.53NDND62101 (84)2.00.4813
11bNDND35123 (141)3.50.50NDND21191 (226)9.00.856
42bNDND10116 (105)11.60.33NDND682 (63)14.50.5728
43bNDND1030 (30)3.00.29NDND646 (46)9.20.531
70bNDND1096 (83)9.60.29NDND5126 (121)23.10.5416
73bNDND5074 (79)1.60.48NDND4487 (94)2.20.675
82bNDND246529 (573)2.70.49NDND275532 (514)2.20.614
  • a Ratio denotes sample signal/cutoff. ND, not done.

  • b These types were not included in the positive controls.