In vitro activity of three echinocandin antifungal agents against fluconazole-resistant isolates of Candida speciesa

SpeciesNo. of isolates testedResults for:b
MIC90% ≤ 2MIC90% ≤ 2MIC90% ≤ 2
C. albicans 410.061000.061000.03100
C. glabrata 1100.121000.061000.015100
C. krusei 1460.121000.251000.06100
All Candida spp.31511000.251000.5100
  • a MICs were determined in RPMI broth with 24-h incubation and prominent-inhibition endpoint. Data were compiled from reference 54.

  • b % ≤ 2, percentage of isolates for which the MIC was 2 μg/ml or less. See Table 1 for abbreviations.