TABLE 2.

External evaluation with isolates whose lineages were preidentifieda

Cutoff and resultNo. (%) of isolates with the indicated result by:
24-locus MIRU-VNTR typing + spoligotyping15-locus MIRU-VNTR typing + spoligotyping24-locus MIRU-VNTR typing15-locus MIRU-VNTR typing
Cutoff of 0.17
    Lineage confirmationb319 (72.2)278 (62.9)240 (54.3)160 (36.2)
    No match123 (27.8)163 (36.9)199 (45.0)282 (63.8)
    Conflictc0 (0.0)1 (0.2)3 (0.7)0 (0.0)
Cutoff of 0.3
    Lineage confirmationb419 (94.8)403 (91.2)392 (88.7)327 (74.0)
    No match8 (1.8)32 (7.2)36 (8.1)106 (24.0)
    Conflictc15 (3.4)7 (1.6)14 (3.2)9 (2.0)
  • a Best-match-based analyses were performed with the 442 isolates with a preidentified lineage from the Brussels-Capital Region collection.

  • b For lineage confirmation data, percentages correspond to sensitivity of lineage identification, defined here as the proportion of correct best matches identified among the test samples.

  • c The specificity for lineage identification equals 100 − conflict (in percent). Specificity is defined here as the portion of correct best matches found among the total best matches identified.