Interlaboratory agreement for caspofungin susceptibility data with 30 isolates of Candida spp.a

Test conditionsEndpointVisual readingsSpectrophotometer results
Agreement range (%)Excellent agreement (%)Agreement range (%)Excellent agreement (%)
RPMI, 24 hMIC0 or IC9037.5-100.033.336.6-93.33.3
MIC2 or IC5064.7-100.073.326.6-100.053.3
RPMI, 48 hMIC0 or IC9044.1-100.036.733.3-86.70.0
MIC2 or IC5026.4-100.043.340.0-96.720.0
RP-G, 103 yeasts/ml, 24 hMIC0 or IC9029.4-
MIC2 or IC5053.1-
RP-G, 103 yeasts/ml, 48 hMIC0 or IC9041.1-
MIC2 or IC5038.2-100.026.736.6-96.736.7
RP-G, 105 yeasts/ml, 24 hMIC0 or IC9038.2-100.036.730.0-100.020.0
MIC2 or IC5041.1-94.126.753.3-100.040.0
RP-G, 105 yeasts/ml, 48 hMIC0 or IC9035.2-
MIC2 or IC5040.6-100.016.730.0-100.030.0
AM3, 24 hMIC0 or IC9056.2-
MIC2 or IC5043.7-
AM3, 48 hMIC0 or IC9048.3-
MIC2 or IC5018.7-100.056.720.0-96.716.7
  • a Agreement range, percentage of results within excellent agreement range across all 30 isolates; excellent agreement, percentage of isolates with ≥90% interlaboratory agreement.