TABLE 1.

ST6Gal I-expressing cells are superior to MDCK cells in the isolation of human influenza viruses from clinical samplesa

Virus typeVirus isolateYr of isolationAntigenic propertyVirus titer (PFU/ml)
MDCK cellsST6Gal I cells
H3N212004A/Fujian/411/2002-like3.4 × 1045.5 × 105
22004A/Fujian/411/2002-like<6.32.8 × 102
32004A/Fujian/411/2002-like<6.31.0 × 102
42004A/Fujian/411/2002-like<6.31.9 × 102
52003A/Fujian/411/2002-like<6.36.9 × 10
62001A/Panama/2007/99-like9.2 × 1041.0 × 106
71999A/Sydney/5/97-like<6.31.0 × 102
81999A/Sydney/5/97-like2.0 × 1022.2 × 103
H1N192002A/New Calledonia/20/99-like1.1 × 1022.6 × 104
102002A/New Calledonia/20/99-like4.3 × 1041.8 × 105
112002A/New Calledonia/20/99-like1.3 × 1026.3 × 102
122002A/New Calledonia/20/99-like2.5 × 1031.1 × 104
132002A/New Calledonia/20/99-like6.31.3 × 10
142000A/Beijing/262/95-like2.0 × 1023.3 × 103
152000A/Beijing/262/95-like4.0 × 104.5 × 102
B162003B/Shandong/7/97-like<6.36.3
172003B/Shandong/7/97-like<6.35.6 × 102
182003B/Shandong/7/97-like<6.33.1 × 10
192003B/Shandong/7/97-like<6.31.9 × 102
202002B/Shandong/7/97-like2.4 × 1061.5 × 107
  • a Nasal or pharyngeal swabs shown to be influenza virus-positive by a rapid diagnosis kit were used for virus titration.