TABLE 3.

NAAT performance statistics for Neisseria gonorrhoeae

Test% (no. of positive samples confirmed/total no. of positive samples) (CIa)
SensitivitySpecificityPPVNPV
First 500Total 1,000First 500Total 1,000First 500Total 1,000First 500Total 1,000
ProbeTec SDA80 (4/5) (28.4-99.5*)80 (12/15) (51.9-95.7*)100 (495/495) (99.3-100**)100 (985/985) (99.6-100*)100 (4/4) (39.8-100**)100 (12/12) (73.5-100**)99.8 (495/496) (98.9-99.9*)99.7 (985/988) (99.1-99.9*)
Aptima Combo2100 (5/5) (47.8-100**)100 (15/15) (78.2-100**)100 (495/495) (99.3-100**)100 (985/985) (99.6-100**)100 (5/5) (47.8-100**)100 (15/15) (78.2-100**)100 (495/495) (99.3-100**)100 (985/985) (99.6-100**)
Roche Amplicor PCR100 (5/5) (47.8-100**)NAb98.8 (489/495) (97.4-99.6*)NA45.5 (5/11) (16.7-76.6*)NA100 (489/489) (99.2-100*)NA
  • a *, 95% confidence interval (CI); **, 97.5% CI.

  • b NA, not applicable.