TABLE 4.

Characteristics of MBL-producing strains and selected clinical data

Species (no. of strains)RAPD typeMBL typea (No. of strains)No. of aac(6′)-Ib-a positive strainsHospitalWardb (no. of strains)Antibiogramc (no. of strains)
P. aeruginosa (22)aIMP-1 (5)4BICU (1), NICU (1), pediatrics 7E (3)GM, MINO, ST, CP (4), GM, ST, CP (1)
bIMP-1 (6)6BInternal medicine 11E (2), internal medicine 13E (1), internal medicine 8E (1), pediatrics 7E (2)GM, MINO, ST, CP (6)
cIMP-1 (1)0BInternal medicine 11E (1)GM, MINO, LVFX, ST, CP (1)
dIMP-1 (1)1BUrology 8W (1)GM, MINO, ST, CP (1)
eIMP-1 (1)0BUrology 8W (1)MINO, ST, CP (1)
fIMP-1 (2)2BUrology 8W (2)GM, AMK, MINO, LVFX, ST, CP (1), GM, MINO, LVFX, ST, CP (1)
gIMP-1 (1)0CEmergency 1S (1)GM, MINO, LVFX, ST, CP (1)
hIMP-1 (1)0CEmergency 1S (1)GM, AMK, MINO, LVFX, ST, CP (1)
iIMP-1 (1)0CPlastic surgery 4C (1)GM, MINO, LVFX, ST, CP (1)
jIMP-1 (2)2HUrology 5W (1), internal medicine MICU (1)GM, MINO, LVFX, ST, CP (2)
kVIM-2 (1)1IInternal medicine 6E (1)GM, MINO, LVFX, ST, CP (1)
A. baumannii (18)AIMP-1 (8)8AInternal medicine 115NS (8)GM, ST, CP (8)
BIMP-1 (1)1COtolaryngology 7E (1)GM, CP (1)
CIMP-1 (1)1FCardiac surgery ICU (1)ST, CP (1)
DIMP-1 (1)1FBrain surgery SCU (1)ST, CP (1)
EIMP-1 (1)1HInternal medicine 7E (1)CP (1)
F1IMP-2 (5)0JSurgery W6 (3), brain surgery W7 (2)ST, CP (5)
F2IMP-2 (1)0KInternal medicine 5A (1)GM, ST, CP (1)
A. junii (1)IMP-1 (1)1COtolaryngology 7E (1)GM, ST (1)
A. calcoaceticus (1)IMP-1 (1)0JInternal medicine ICU (1)AMK, ST (1)
A. johnsonii (1)IMP-2 (1)0KInternal medicine 5A (1)ST (1)
S. marcescens (44)1IMP-1 (2)0ANeurology 75NS (1), urology 65NS (1)MINO, LVFX, ST, CP (1) MINO, LVFX, CP (1)
2IMP-1 (1)0CUrology 7F (1)MINO, ST, CP (1)
3IMP-1 (41)0CEmergency 1S (14), internal medicine CCU (13), urology 7F (5), brain surgery 6F (2), cardiac surgery 4S (2), internal medicine 3S (2), plastic surgery 5C (2), surgery 4F (1)CP (7), AMK (1), MINO (1), MINO, CP (1)
Providencia rettgeri (3)1IMP-1 (2)2CUrology 7F (2)ST, CP (2)
2IMP-1 (1)1CInternal medicine 83 (1)MINO, LVFX, ST (1)
Citrobacter freundii (4)1IMP-1 (4)4CInternal medicine CCU (3), internal medicine 3S (1)CP (1)
Morganella morganii (1)IMP-1 (1)1CUrology 7F (1)MINO, LVFX, ST (1)
Enterobacter cloacae (1)VIM-2 (1)0DPediatrics E6 (1)MINO, ST, CP (1)
  • a MBL types: IMP-1, IMP-1-group MBLs, including IMP-1, IMP-3, IMP-6, and IMP-10; IMP-2, IMP-2-group MBLs, including IMP-2, IMP-8, and IMP-11; VIM-2, VIM-2 MBLs.

  • b ICU, intensive care unit; NICU, neonatal intensive care unit; MICU, medical intensive care unit; SCU, surgical care unit; CCU, coronary care unit.

  • c Antibiogram: AMK, amikacin (64 μg/ml); GM, gentamicin (16 μg/ml); MINO, minocycline (16 μg/ml); LVFX, levofloxacin (8 μg/ml); ST, sulfamethoxazole-trimethoprim (4 μg/ml); CP, chloramphenicol (32 μg/ml).