TABLE 2.

Drug stability study with BACTEC MGIT 960 systema

LVX concn (μg/ml)TreatmentNo. of days to positivity for reading no.
12345Avg
0.5Fresh16.019.818.217.221.118.5
4°C24.523.416.225.923.522.7
37°C24.521.116.827.918.821.8
0.25Fresh5.35.45.84.66.15.4
4°C6.05.35.56.14.35.4
37°C4.74.95.24.84.84.9
  • a Results of the drug stability studies in the BACTEC MGIT 960 system for LVX at two subinhibitory concentrations in freshly prepared drug-containing medium, medium stored at 4°C for 14 days, and medium stored at 37°C for 14 days inoculated with M. tuberculosis strain H37Rv. The number of days to positivity indicates the number of days to achieve detectable growth with the BACTEC MGIT 960 instrument. A control with no drug was also tested and became positive in 3.3 to 3.5 days.