TABLE 3.

Results of Q-PCR positivity and B. melitensis DNA loads in blood and serum samples over time for the three groups of patients

Patient groupa (n)No. of positive Q-PCR samples/total samples analyzed (B. melitensis DNA loadb) at the following point:
BaselineTreatment periodPosttreatment follow-up
BloodSerumBloodSerumBloodSerum
A (8)12/39 (244 ± 253)7/38 (432 ± 505)9/27 (316 ± 479)4/26 (650 ± 767)1/29 (15)2/29 (2,516 ± 2,109)
B (9)14/67 (515 ± 1,524)12/65 (243 ± 222)1/18 (599)2/18 (142 ± 180)7/33 (128 ± 199)6/33 (384 ± 218)
C (18)5/36 (171 ± 136)2/36 (53 ± 11)
  • a Group A, focal-disease patients; group B, nonfocal-disease patients; group C, asymptomatic subjects.

  • b Expressed as mean copies per milliliter ± SD.