TABLE 2.

Performance characteristics of AccuProbe tests with adjusted cutoff values

Cutoff RLU and organism% (95% CI)
SensitivitySpecificityPositive predictive valueNegative predictive value
30,000
    S. aureus80.8 (74.69-85.97)98.7 (97.29-99.47)95.9 (91.75-98.34)93.1 (90.62-95.01)
    S. pneumoniae97.9 (93.95-99.56)100 (98.06-100)100 (97.38-100)98.4 (95.48-99.67)
55,000
    Enterococcus98.2 (90.28-99.95)99.1 (97.3-99.81)94.7 (85.38-98.9)99.7 (98.27-99.99)
    Group A streptococcus100 (81.47-100)100 (98.87-100)100 (81.47-100)100 (98.87-100)
    Group B streptococcus100 (90.26-100)99.7 (98.35-99.99)97.3 (85.84-99.93)100 (98.9-100)