TABLE 1.

Comparison of phenotypes and genotypes of erythromycin-resistant GAS isolatesa

PhenotypebGenotypeNo. of isolatesMIC (μg/ml)
ErythromycinClindamycin
90%Range90%Range
MmefA33328-320.060.06-0.125
iMLSBermB1≥1,0240.25
iMLSBermTR8≥1,0244-≥10240.250.06-0.5
cMLSBermB5≥1,024256-≥10245121-512
Unknown2≥1,0240.06-0.125
  • a A total of 49 isolates were tested.

  • b Abbreviations: M, efflux; iMLSB, inducible MLSB resistance; cMLSB, constitutive MLSB resistance.